妊娠高血圧とintra uterine growth retardation(IUGR)に関する研究 : ラット子宮胎盤の動脈系血管構築

概要

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An important subject in current perinatal medicine is clarifying the factors behind, as well as the prevention of, intra uterine growth retardation (IUGR) and accompanying small for dates infants (SFD). Since the conditions of pregnancy hypertension in stroke prone spontaneously hypertensive rats (SHRSP) are similar to those in humans, in this study on clarifying the factors causing IUGR-SFD we examined the placenta of pregnant SHRSP : In order to clarify utero-placental vascular construction and the hemodynamics of maternal blood flow in the rats, we prepared resin plastic as well as microscopical specimens, using a contrast medium of 5% gelatin and 0.1% tripan blue in 35% barium sulfate injected into the abdominal aorta and umbilical veins. The following results have been obtained so far. The arcuate arteries branch off from the uterine artery, and then fork in three directions. Relatively fine blood vessels branch off from the arcuate artery to the peripheral arteries and pass through the uterine surface. These blood vessels go from the arcuate to the basal, and then to the radial artery. A relatively thick vessel, or "spiral artery, " branches off from the arcuate artery and passes through the central region. Reaching the fetal side, the vessel changes its course by 90° and runs radially.
近畿大学の論文
1987-12-30