<原著>墨汁およびラテックス粒子を投与したウサギ角膜実質の電子顕微鏡的研究

概要

論文の詳細を見る
In order to know the fine structure of fibroblasts and the origin of phagocytic cells in the corneal stroma of the rabbit, normal and Indian ink- or latex beads-injected corneas were studied with light and electron microscopies. The following results have obtained. In the normal stroma, fibroblasts lying between the lamellae of collagen fibers are spindle-shaped and have long cytoplasmic processes. These processes are in contact with those of neighboring fibroblasts by gap junctions. The fibroblasts formed networks by this junction which might play an important role in synchronizing the functions of the cells. The shapes of all the dots of injected Indian ink or injected latex beads remain unchanged for at least 6 months or much longer time after the injection. Indian ink or latex beads are found inside the corneal fibroblasts by pinocytosis on the 3rd-4th days after the injection. Six months after the injection most cells still retained have Indian ink and they have become polygonal in shape, but some are still spindle-shaped. These endocytosing cells gather together, and well developed interdigitations and gap junctions are seen between them. Thus it is concluded that in the cornea, most of the cells taking up injected Indian ink and latex beads are stromal cells (fibroblasts), and that these particles remain in the cytoplasms of these cells for a long time.
近畿大学の論文
1987-03-25