<原著>コラーゲン線維形成速度に対する架橋量及び末端テロペプチドの影響

概要

論文の詳細を見る
The parameter of the amount of cross-linkage, β/α, determined by SDS polyacrylamide electrophoresis for the collagens obtained by several methods of extraction from normal and lathyritic rat skin spread over wide range. The rate of fibril formation of these collagens was measured by turbidity method in 0.05 M Tris-HCl buffer pH 7.5 containing 0.15 M and 1 M NaCl. The rate of fibril formation was largely accelerated by cross-linkage. The effect of the existence of telopeptides on the rate of fibril formation was examined with lathyritic collagens. The effect of telopeptides was found to be scarce, whereas the effect of the amount of cross linkage on the rate of fibril formation was considerable.
近畿大学の論文
1982-06-25