Pseudomyxoma peritoneiによる粘質物(第 2 報) : シアロムコ多糖体の単離と性質
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概要
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The glycoprotein obtained from a peritoneal pseudomyxomatous gelatinous substance was treated with a protease and fractionated with ethanol, and a fraction rich in sialic acid was purified by the gel filtration on Sephadex G-50 and G-100. The sialomucopoly-saccharide so obtained is an active Le^a-specific substance and it contains 31.8% of N-acetyl neuraminic acid, 18.2% of D-galactosamine, 13.4% of D-glucosamine, 13.7% of D-galactose, 3.7% of L-fucose and 12.0% of peptide composed of ten kinds of amino acids. It is concluded that the both hexosamines exist as N-acetyl derivatives. The major part of peptide moiety is taken by threonine, proline and phenylalanine. The molar ratio of component carbohydrates and amino acids was as follows; sialic acid : galactosamine : glucosamine : galactose : fucose : threonine : proline : phenylalanine was about 4 : 4 : 3 : 3 : 1 : 1 : 1 : 0.8.
- 共立薬科大学の論文
- 1966-05-20
共立薬科大学 | 論文
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