<Original Report>A NEW ATIGEN IN LEUKEMIA L1210 SUBLINE (RESISTANT TO METHYLGLYOXAL-BIS-GUANYLHYDRAZONE)

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概要

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• この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。Using paired label radio-antibody method which γ-globulin from antiserum was labeled with ^<125>I and γ-globulin from normal serum was labeled with ^<131>I, the following conclusions had been gotten : 1). Both L1210 and the resistant subline to methylglyoxal-bis-guanylhydrazone (L1210/CH_3-G) cells are immunogenic in vitro and elicit a demonstrable humoral antibody response in the DBA/2Ha-DD mice. 2). The resistant subline L1210/CH_3-G cells is more immunogenic than L1210 cells in DBA/2Ha-DD mice. 3). The antigenic specificity of L1210 is different from that of L1210/CH_3-G cells, although both cell lines share some common antigens. 4). Therefore, the data support the hypothesis that new antigen(s) have been produced in drug-resistant sublines of leukemia L1210.

• 京都大学の論文
• 1974-03-30

著者

• Kitano Morihisa

  Department Of Thoracic Surgery Aizawa Hospital

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• A NEW ATIGEN IN LEUKEMIA L1210 SUBLINE (RESISTANT TO METHYLGLYOXAL-BIS-GUANYLHYDRAZONE)
• Invited Commentary

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