外傷後ストレス障害(PTSD)の精神生物学

概要

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"A certain subset of people exposed to traumatic stress develop long-term changes in behavior and in their neurobiological syetems. Symptoms may include dissociative flashbacks and intrusive memories, sleep disturbance, nightmares, avoidance reactions, abnormal startle reactions, and physiological hyperresponsiveness to reminders of the original trauma, etc. Current evidence concerning the neurotransmitters and central structures which are likely involved in PTSD are considered along with the drugs which have been found to be effective in treating some of the symptoms of the disorder. The changes which initially occur during the traumatic experience and which set the stage for PTSD are discussed from the point of view of their being adaptive in the early stages of the crisis with abnormality developing over time if the vicious cycle of hyperarousal and further glucocorticoid secretion cannot be broken."
岡山理科大学の論文