Cardiovascular responses to apelin-12 injection into the ventral medullary surface in rats

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概要

• 論文の詳細を見る

• We examined cardiovascular responses to the injection of apelin-12 (AP12) into the ventral medullary surface (VMS) in Wistar rats anesthetized with ethyl carbamate and pentobaribital sodium. We found that the injection of AP12 into the VMS induced pressor and tachycardiac responses. With stepwise increases in the dose (1nmol/kg. 5 nmol/kg. lOnmol/kg), the pressor and tachycardiac responses increased dose-dependently. The present results suggest that apelin peptides may play some roles in central ardiovascular regulation.

• 群馬大学の論文

著者

• TATEMOTO Kazuhiko

  Department of Molecular Physiology, Institute for Molecular and Cellular Regulation, Gunma Universit

• Takayama Kiyoshige

  Department Of Laboratory Sciences Gunma University School Of Health Science

• MOTEGI Shunichi

  Department of Laboratory Sciences, Gunma University School of Health Sciences

• KUMAKI Iku

  Department of Laboratory Sciences, Gunma University School of Health Sciences

• HOU Xing

  Department of Molecular Physiology, Institute for Molecular and Cellular Regulation, Gunma Universit

• Tatemoto Kazuhiko

  Department Of Molecular Physiology Institute For Molecular And Cellular Regulation Gunma University

• Kumaki Iku

  Department Of Laboratory Sciences Gunma University School Of Health Sciences

• Motegi Shunichi

  Department Of Laboratory Sciences Gunma University School Of Health Sciences

• Hou Xing

  Department Of Molecular Physiology Institute For Molecular And Cellular Regulation Gunma University

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