Pathogenesis and the role of Ca2+ overload during myocardial ischemia/reperfusion
スポンサーリンク
概要
著者
-
Hayashi Hideharu
Department Of Internal Medicine Iii Hamamatsu University School Of Medicine
-
Hayashi Hideharu
Department Of Humoral Regulation Research Institute Of Environmental Medicine Nagoya University
-
Hayashi Hideharu
Department Of Cardiology Hamamatsu Medical Cente
関連論文
- Protein Kinase A Catalytic Subunit Alters Cardiac Mitochondrial Redox State and Membrane Potential Via the Formation of Reactive Oxygen Species
- Protein Phosphatase Inhibitor-1 Augments a Protein Kinase A-Dependent Increase in the Ca^ Loading of the Sarcoplasmic Reticulum Without Changing Its Ca^ Release
- PJ-788 Calmodulin Regulates Mitochondrial Ca2+ Homeostasis by Activating Mitochondrial Na+/Ca2+ Exchanger(PJ132,Heart Failure, Basic (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- PJ-070 The Different Modulation of SR Ca^ Release Events by Protein Kinase A and Protein Phosphatase Inhibitor-1 in Permeabilized Rat Myocytes(PJ012,Calcium Handling, Cardiac Function (Basic) (M),Poster Session (Japanese),The 73rd Annual Scientific Me
- PJ-062 Evaluation of Low- Non- Enhancement Myocardium on Cardiac Multi-Detector Row Computed Tomography (MDCT) in the Diagnosis of Myocardial Viability(PJ011,CT/MRI (Myocardium) 4 (I),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Jap
- PE-309 Anemia in Chronic Kidney Disease (CKD) Deteriorates Left Ventricular Diastolic Function without Increasing Left Ventricular Mass Index (LVMI)(PE052,Kidney/Renal Circulation/CKD 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of Th
- OE-133 Thiol-Mediated Responses Contribute to the Biphasic Effects of Nitric Oxide (NO) on Mitochondrial Permeability Transition Pore(OE23,Heart Failure (Pathophysiology) (M),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese C
- FRS-065 Regulation of Mitochondrial Permeability Transition Pore by Glycogen Synthase Kinase 3β (GSK3β) is Related to Mitochondria-bound Hexokinase Activity(FRS13,Novel Molecular Mechanisms of Heart Failure 2 (M),Featured Research Session (English),The 73
- FRS-045 Transient Opening of Mitochondrial Permeability Transition Pore by Reactive Oxygen Species Protects Cardiac Myocytes by Modulating Mitochondrial Ca^(FRS9,Novel Mechanisms of Myocardial Ischemia (IHD),Featured Research Session (English),The 73r
- The usefulness of delayed enhancement magnetic resonance imaging for diagnosis and evaluation of cardiac function in patients with cardiac sarcoidosis
- PJ-810 Interpretation of Elecrocardiographic Abnormalities in Hypertrophic Cardiomyopathy (HCM) Using Cardiac Magnetic Resonance Imaging (CMR)(Cardiomyopathy, basic / clinical(07)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japan
- PJ-809 Delayed Enhancement in Cardiac Magnetic Resonance (CMR) Relates to Eccentricity of Left Ventricular Hypertrophy in Hypertrophic Cardiomyopathy(Cardiomyopathy, basic / clinical(07)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of th
- PJ-734 Global and Regional Analyses of 99mTc-sestamibi (MIBI) Imaging and Cardiac Magnetic Resonance Imaging (MRI) in Dilated Cardiomyopathy (DCM)(Nuclear cardiology(10)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circul
- PJ-627 Anemia Augments Left Ventricular Dysfunction in Patients with Chronic Kidney Disease(Cardiac function, basic/clinical(04)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-145 Intravenous Glutathione(GSH), a Novel Prophylaxis against Contrast-induced Nephropathy(CIN)(Kidney/Renal circulation(05)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-115 Protein phosphatase inhibitor 1 (l-1) augments a protein kinase A-dependent increase in SR Ca2+ loading without changing Ca2+ spark(Heart failure, basic(05)(M),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation
- PJ-093 Extracellular but not Intracellular Acidosis Suppresses Endothelial Function by Inhibiting Intracellular Calcium Responses(Endothelium(03)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-217 Different Effects of Palmitoyl-L-carnitine and Palmitoyl-CoA on Mitochondrial Function in Rat Myocytes(Metabolism/Biochemistry/Energetics(02)(M),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-094 Local Control of Mitochondrial Membrane Potential and Permeability Transition Pore by Calcium and Calmodulin in Rat Ventricular Myocytes(Heart failure, basic(02)(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circ
- OJ-051 Dual Effects of Nitric Oxide on Mitochondrial Permeabillity Transition in Rat Ventricular Myocytes(Myocarditis, basic/clinical(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- OE-273 The Serum Soluble Interleukin-2 Receptor (sIL-2R) is an Useful Marker to Evaluate the Involvement and the Activity of Cardiac Sarcoidosis.(Cardiomyopathy, basic/clinical(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Ja
- PE-114 Usefulness of ST Segment Analyses to Diagnose AVRT in Paroxysmal Supravebtricular Tachycardia (PSVT)(Arrhythmia, diagnosis/pathophysiology/EPS-08, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-077 Blocking Effect of SN-6, a Novel Benzyloxyphenyl Derivative, on Na^+/Ca^ Exchange Current in Single Guinea-pig Cardiac Ventricular Myocytes(Cardiovascular pharmacology, basic/clinical-3 (H) PE13,Poster Session (English),The 70th Anniversary Ann
- Excessive nitric oxide production and cardiac dysfunction in patients with chronic renal failure
- Evaluation of right and left ventricular function by quantitative blood-pool SPECT (QBS) : Comparison with conventional methods and quantitative gated SPECT (QGS)
- PJ-337 The significance of Delayed Enhancement MRI to Evaluate Global and Local Left Ventricular Wall Function in Hypertrophic Cardiomyopathy(Cardiomyopathy, basic/clinical-5 (M) PJ57,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meetin
- OJ-002 Influence of Genetic Polymorphisms of OATP-C on Cholesterol Lowering Effect of Pravastatin(Cardiovascular pharmacology, basic/clinical-2 (H) OJ1,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
- 4 Inhibition of Type-5 Phosphodiesterase : Promising Therapy for Pulmonary Hypertension(Which drug is useful for the treatment of pulmonary hypertension?,Topic 4 (TP4) (M),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Long-Term Survival in Patients with Pulmonary Hypertension Treated with a Type 5 Phosphodiesterase Inhibitor Sildenafil(Pulmonary Circulation 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OE-271 Pharmacokinetic and pharmacodynamic interactions between simvastatin and diltiazem in patients with hypercholesterolaemia and hypertension(Cardiovascular Pharmacology, Basic/Clinical 1 (H) : OE34)(Oral Presentation (English))
- Assessment of Forearm Reactive Hyperemia Using Near-Infrared Time-Resolved Spectroscopy : A New Tool to Evaluate Endothelial Function
- Large Quantities of NO Inhibit Agonist-Induced Endothelial Cell Ca^ Responses via a Peroxynitrite Pathway
- Inhibition of Type 5 Phosphodiesterase : Promising Therapy for Pulmonary Hypertension
- A potential role of sildenafil in the management of pulmonary hypertension
- A novel nonpeptide bradykinin receptor agonist in the regulation of endothelial calcium signaling and coronary artery tone
- Nitric oxide : a negative feedback on endothelium-derived vascular relaxing factors
- PJ-541 The Species Dependence of Non-genomic Effects of Aldosterone : Analysis of [Na^+] _i and pH_i in Rat and Guinea Pig Ventricular Myocytes(Neurohumoral factors-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Involvement of [Na^+]_i and Na^+/Ca^ Exchanger in the Negative Inotropic Effect of a Na^+ Channel Blocker in Guinea-pig Ventricular Myocytes(Arrhythmia, Pharmacological Therapy 1 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Soci
- PJ-458 The Acute Phase Effects of Combined Reperfusion Therapy by tPA and Angioplasty for Acute Myocardial Infarction : Analysis by Hamamatsu-PACT Trial(Acute Myocardial Infarction, Clinical (Diagnosis/Treatment) 12 (IHD) : PJ76)(Poster Session (Japanese)
- Pathogenesis and the role of Ca2+ overload during myocardial ischemia/reperfusion
- Interaction between Amlodipine and Simvastatin in Patients with Hypercholesterolemia and Hypertension
- USEFULNESS OF THALLIUM-201 MYOCARDIAL PERFUSION IMAGES FOR JUDGING THE EFFECT OF REDUCING INFARCT SIZE BY PTCR : COMPARING WITH LEFT VENTRICULOGRAPHY IN CHRONIC PHASE : Ischemic Heart Disease (II), Coronary Circulation : II : 48 Annual Scientific Meeting,
- Arrhythmogenic Effects of Arsenic Trioxide in Patients With Acute Promyelocytic Leukemia and an Electrophysiological Study in Isolated Guinea Pig Papillary Muscles
- PJ-593 Carotid Intima-media Thickness Can Predict Coronary Artery Disease Better Than Brachial-ankle Pulse Wave Velocity(Angina pectoris, basic/clinical-5 (IHD) PJ100,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese
- A Novel Noninvasive Method to Evaluate Baroreceptor Sensitivity (BRS) Using Impulse Response Function (IRF) with Autoregression Model
- I-123 MIBG Scintigraphy for the Evaluation of Cardiac Sympathetic Nerve Activity (SNA) : Comparison with Impulse Response Function (IRF)
- Sildenafil, a Type-5 Phosphodiesterase Inhibitor, Improves Vascular Response to Reactive Hyperemia in Patients with Raynaud's Phenomenon
- PE-524 The Urine Lipid Peroxides (LPO) is a New Landmark of Renal Oxidative Stress in CIN : Effects of NAC(Kidney/Renal circulation-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-048 Usefulness of Delayed Enhancement Magnetic Resonance Imaging to Differentiate Dilated phase of Hypertrophic Cardiomyopathy from Dilated Cardiomyopathy(Cardiomyopathy, basic/clinical-2, The 71st Annual Scientific Meeting of the Japanese Circulation
- PE-612 Non-genomic Effects of Aldosterone on Intracellular Ion Regulation and Cell Function in Rat Ventricular Myocytes(Neurohumoral factors-2 (H) PE108,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation So
- PE-597 Protein Kinase A (PKA)-induced Alterations in Mitochondrial Function is Regulated by Reactive Oxygen Species in Rat Cardiomyocytes(Metabolism/Biochemistry/Energetics-2 (M) PE105,Poster Session (English),The 70th Anniversary Annual Scientific Meetin
- PE-187 The Interaction of NO and 20-HETE in the Reduction of Cerebral Blood Flow Following Subarachnoid Hemorrhage in Rats(Cerebrovascular circulation/Stroke-2 (IHD) PE32,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japan
- PE-073 Novel Property of Amlodipine to Improve Disturbed Endothelial Barrier Function by Mechanisms Other than the Effect on Voltage-dependent Calcium Channel(Cardiovascular pharmacology, basic/clinical-3 (H) PE13,Poster Session (English),The 70th Anniver
- PE-028 The Extensive Epicardial Delayed Potential Relates to Induction of Ventricular Fibrillation in Asymptomatic Patients with Brugada Syndrome(Arrhythmia, diagnosis/pathophysiology/EPS-7 (A) PE5,Poster Session (English),The 70th Anniversary Annual Scie
- Usefulness of Delayed Enhancement Magnetic Resonance Imaging for Detecting Cardiac Rupture Caused by Small Myocardial Infarction in a Case of Cardiac Tamponade
- Different Actions of Cardioprotective Agents on Mitochondrial Ca^ Regulation in a Ca^ Paradox-Induced Ca^ Overload
- Modification of SR Ca^ Release by FK506 Induces Defective Excitation-Contraction Coupling Only When SR Ca^ Recycling is Disturbed (Cardiovascular Pharmacology, Basic/Clinical 3 (H), The 69th Annual Scientific Meeting of the Japanese Circulation So
- Left Ventricular Pseudo-False Aneurysm Detected With ECG-Gated Multidetector Computed Tomography and Cardiac Magnetic Resonance Imaging
- Usefulness of Stress Myocardial Perfusion Imaging for Evaluating Asymptomatic Patients After Coronary Stent Implantation
- OJ-216 The Risk of Thrombogenesis in Chronic Atrial Flutter after Catheter Ablation : Evaluation by Left Atrial Appendage Function and Thrombogenic Activities(Blood Coagulation/Fibrinolysis (IHD) : OJ24)(Oral Presentation (Japanese))
- Is SPECT Cost-Effective in Managing Ischemic Heart Disease (IHD) in Japan? Comparison with Exercise ECG-Testing (EET) and Coronary Angiography (CAG)
- 3 Stress Myocardial SPECT Is Cost-effective in Diagnosis And Management of Ischemic Heart Disease (IHD) in Diagnosis Procedure Combination (DPC) Era(Plenary Session 6 (PL6) (I) : Role of Diagnostic Imaging in the Management of Coronary Artery Disease and
- The Usefulness of Delayed Enhancement Magnetic Resonance Imaging for Diagnosis of Cardiac Sarcoidosis (Cardiomyopathy, Clinical 5 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Differential Diagnosis of Dilated Phase of Hypertrophic Cardiomyopathy by Using Delayed Enhancement Magnetic Resonance Imaging (DE-MRI)(Cardiomyopathy, Clinical 7 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Intracoronary Administration of Acetylcholine Directly Modifies ST-T Waves (ECG/Body Surface Potential Mapping/Holter 5 (A), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Discordance Between Myocardial Perfusion Imaging SPECT (MPI) and Pressure Wire-derived Fractional Flow Reserve (FFRmyo) in Intermediate Coronary Stenoses(Nuclear Cardiology 4 (I), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Non-genomic Effects of Aldosterone on Intracellular Na^+ Concentration in Rat Ventricular Myocytes : Analysis Using Sodium-green With Laser Scanning Confocal Microscopy(Neurohumoral Factors 3 (H), The 69th Annual Scientific Meeting of the Japanese Circula
- A Selective Inhibitor of Na^+/Ca^ Exchanger, SEA0400, Preserves Cardiac Function and High-energy Phosphates Against Ischemia/reperfusion Injury(Cardiovascular Pharmacology, Basic/Clinical 1 (H), The 69th Annual Scientific Meeting of the Japanese Circu
- Direct Effects of Protein Kinase A on Mitochondrial Membrane Potential and Redox State are Mediated by Reactive Oxygen Species(ROS)(Metabolism/Biochemistry/Energetics 2 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Post-challenge Hyperinsulinemia Rather Than Hyperglycemia is Associated with the Severity of Coronary Artery Disease in Non-diabetic Patients(Diabetes/Obesity 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Opening of Mitochondrial Permeability Transition Pore by Reactive Oxygen Species Protects Myocardium from Ischemia/Reperfusion Injury(Myocardial Ischemia-reperfusion, Basic 1 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-498 The Arrhythmogenic Effects of Arsenate in Patients with Acute Promyelocytic Leukemia and Electrophysiological Study in Guinea Pig Papillary Muscles(Arrhythmia, Basic 5 (A) : PJ83)(Poster Session (Japanese))
- PJ-383 The Mitochondrial Ca Accumulation is Necessary for Cell Protection by Ca Preconditioning(Metabolism/Biochemistry/Energetics 2 (IHD) : PJ64)(Poster Session (Japanese))
- PE-213 Contribution of Mitochondrial Na^+/Ca^ Exchange to the Regulation of Mitochondrial Ca^ in Rat Ventricular Myocytes(Metabolism/Biochemistry/Energetics 1 (IHD) : PE37)(Poster Session (English))
- PE-211 Sarcolemmal Na/Ca Exchange and Mitochondria are Both Involved in Ca Paradox Induced Cell Injury : Effects on [Ca]_i and [Ca]_m(Myocardial Ischemia-Reperfusion, Basic and Clinical 2 (M) : PE36)(Poster Session (English))
- PE-037 Myocardial perfusion imaging SPECT (MPI) and pressure wire-derived fractional flow reserve (FFRmyo) are discordant in coronary ischemia(Nuclear Cardiology 5 (I) : PE7)(Poster Session (English))
- Role of Mitochondrial K_ Channel in Protection against Ca Paradox : Evaluation by Cytosolic and Mitochondrial Ca Concentration
- Spatial difference of Ca^ transients in ventricular myocyts of adult and new born rabbits
- OJ-050 Platelet Aggregation in Outpatients Treated with Antiplatelet Drugs for Cardiovascular Diseases Using a New Type of Whole Blood Aggregation Analyzer(Antithrombofic Ttherapy (H) : OJ6)(Oral Presentation (Japanese))
- Difference in the Cardioprotective Mechanisms Between Ischemic Preconditioning and Pharmacological Preconditioning by Diazoxide in Rat Hearts
- Involvement of Mitochondrial K_ Channels (mitok_) and Permeability Transition Pore (mPTP) in the Cardioprotective Action of Hydrogen Peroxide
- The Cardioprotective Effects of Mitochondrial K_ Channels Opener Are Independent of the Mitochondrial Permeability Transition Pore in Perfused Rat Hearts
- The Regulation of Mitochondrial Ca^ by Ca^ Uniporter and Mitochondrial Membrane Potential in Skinned Rat Myocyte
- The Roles of Mitochondrial Permeability Transition Pore in Regulation of Mitochondrial Ca^ Concentration in Skinned Rat Myocytes
- Confocal Imaging of the Opening of Mitochondrial Permeability Transition Pore in Cardiac Myocytes
- Protective Effects of Hydrogen Peroxide Against Ischemia/Reperfusion Injury in Perfused Rat Hearts
- Dual effects of hydrogen peroxide against ischemia/reperfusion injury in perfused rat hearts
- Novel method of confocal imaging of mitochondrial Ca in saponin-permeabilized cardiac myocytes
- Effects of corticotropin-releasing factor relating peptide, urocortin, on cell contraction and Ca^ in isolated rat ventricular myocytes