Immunolocalization of Voltage-Gated Potassium Channel Kv3.4 Subunit in the Cochlea

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概要

• 論文の詳細を見る

• Immunohistochemical localization of voltage-gated potassium channel Kv3.4 subunit was studied in the guinea-pig cochlea. Kv3.4-like immunoreactivity was present in the type I and suprastrial fibrocytes of the spiral ligament and the basal cells of the stria vascularis. Immunostaining was also found in the type II-IV fibrocytes of the spiral ligament and the connective tissue cells of the spiral limbus. In the organ of Corti, Kv3.4-like immunoreactivity was found in the sensory cells and the neighboring supporting cells. The root cells and interdental cells were positively immunostained. Immunoreactivity was also found in the endothelial cells of the blood vessels in the cochlear modiolus. These results suggest that Kv3.4 may participate in the potassium ion recycling mechanism in the cochlea.

• 長崎大学の論文

著者

• KIKUCHI Toshihiko

  Department of Otolaryngology, Nagasaki University School of Medicine

• Ishimaru Kotaro

  Division Of Otorhinolaryngology Department Of Translational Medical Sciences Nagasaki University Gra

• Kikuchi Toshihiko

  Department Of Otorhinolaryngology-head And Neck Surgery Tohoku University Graduate School Of Medicin

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