Immunological Tolerance, Autoimmunity and Host Defense

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概要

• 論文の詳細を見る

• Rearrangement of the antigen-specific lymphocyte receptor genes generates repertoire of T and B cells that can attack any emerging pathogens as well as host tissue itself. This horror autotoxicus has to be removed by mechanisms collectively called self-tolerance. Recent advances in immunological science revealed that there are multiple mechanisms of tolerance both in central and peripheral organs. However, it has become more and more apparent that cellular mechanisms that induce tolerance (inactivation) and activation of lymphocytes are quite similar. Possible mechanisms by which immune system distinguishes self-structure from pathogens will be discussed.

• 長崎大学の論文

著者

• Yui Katsuyuki

  Department Of Molecular Medicine Division Of Immunology Nagasaki University Graduate School Of Biome

• Yui Katsuyuki

  Department Of Medical Zoology And Immunology Nagasaki University School Of Medicine

関連論文

• Cross-presentation of NY-ESO-1 cytotoxic T lymphocyte epitope fused to human heat shock cognate protein 70 by dendritic cells
• Immunological Tolerance, Autoimmunity and Host Defense
• Generation of cytotoxic T lymphocytes by MHC class I ligands fused to heat shock cognate protein 70

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