Studies on the Development of Inflammatory Lesions : I. Influences of Cortisone and Methylandrostendiol on Experimental Tuberculosis

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概要

• 論文の詳細を見る

• この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。In this paper, the author observed the influences of various steroid hormones on tuberculous lesions as a part of the study in the general tissue reaction. Thirty guinea pigs were infected and then administered with several hormones at the 3rd week after the inoculation. At the various periods (the 5th, the 7th, the 10th and 20th week after the infection), the macroscopic and histological findings of the lesions were investigated. The following results were obtained; by the administration of cortisone or MAD (Methylandrostendiol), the patterns of the tuberculous lesions were greatly modified. Multiplication of fibroblasts and infiltration of lymphocytes were inhibited by the administration of cortisone in this experiment. On the other hand, fibroblastic response and proliferation of epithelioid cells were promoted by the administration of MAD according to its periods. Therfore MAD seems to hasten inflammatory process to the productive type. Due to the administration of MAD, a proliferation of small bile ducts of the tuberculous animals was also observed.

• 京都大学の論文
• 1956-06-25

著者

• 天津 正

  Tuberculosis Research Institute Kyoto University

• 天津 正

  the Pathological Division of the Tuberculosis Research Institute, Kyoto University

関連論文

• Tissue Reactions to Coagulated Caseous Substance
• Tissue Reactions Induced by Solid Proteins
• Studies on the Development of Inflammatory Lesions : III. Influence of Cortisone and Methylandrostendiol on the Tissue Reactions Caused dy Fatty Acids and Turpentine.
• Studies on the Development of Inflammatory Lesions : II. Influence of Cortisone and Methylandrostendiol on the Tissue Reactions Caused by Dead Tubercle Bacilli
• Studies on the Development of Inflammatory Lesions : I. Influences of Cortisone and Methylandrostendiol on Experimental Tuberculosis

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