<Originals>Loss of energy consumption during muscular contraction in partially denervated regenerating frog sartorius muscle
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概要
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1. The dynamics of the response of partially denervated regenerating frog sartorius muscle to muscular contraction were investigated by in vivo ^<31>P-NMR spectroscopy. 2. Morphologically, muscle stump became occupied with muscle fibers and showed no significant differences from controls eight weeks after the operation. The frog skeletal muscle seemed to regenerate not only muscle stumps but denervated and innervated sites of the muscle. 3. Compared with innervated and control muscles, denervated regenerating muscle showed low tetanic tension and small changes in the relative concentrations of PCr to β-ATP, Pi to β-ATP, and in intracellular pH value with direct muscle stimulation. 4. These results suggested that partially denervated regenerating muscle may have reduced consumption of high-energy phosphate compounds resulting in a decrease in muscular contraction, or have decreased muscular contractile activity resulting in a reduction in the consumption of high-energy compounds.
- 近畿大学の論文