Functionalized Mesostructured Cellular Foams for Loading and Release of Streptomycin
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概要
- 論文の詳細を見る
Mesostructured cellular foam (MCF) materials were synthesized by microemulsion followed by functionalization with glucose or glutaraldehyde. Successful surface modification was confirmed by Fourier transform infrared, X-ray small-angle diffraction, and nitrogen sorption measurements. The effect of surface chemistry of MCF on the loading and release of streptomycin sulfate was studied in detail. Results indicated that grafting with either glucose or glutaraldehyde cannot only increase the loading amount of drug from 5% to 25% but also change the drug release profile significantly. This work provided an excellent example of controlling drug release by varying the surface chemistry of the materials.
- 公益社団法人 日本化学会の論文
- 2013-03-05
著者
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WU Yiwei
Department of Radiology, Toyama Medical and Pharmaceutical University
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Yu Aimin
Faculty Of Life And Social Sciences Swinburne University Of Technology
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ZHANG Haili
Department of Chemistry, Hubei Normal University
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XU Shaohua
Faculty of Life and Social Sciences, Swinburne University of Technology
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YONG Jiawey
Faculty of Life and Social Sciences, Swinburne University of Technology
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LAI Guosong
Department of Chemistry, Hubei Normal University
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- Functionalized Mesostructured Cellular Foams for Loading and Release of Streptomycin