Issues Related to Recent Dengue Vaccine Development

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概要

• 論文の詳細を見る

• Dengue fever (DF) and dengue hemorrhagic fever (DHF) are mosquito-transmitted diseases of global importance. Despite significant research efforts, no approved vaccines or antiviral drugs against these diseases are currently available. This brief article reviews the status of dengue vaccine development, with particular emphasis on the vaccine strategies in more advanced stages of evaluation; these include traditional attenuation, chimerization and engineered attenuation. Several aspects of these vaccine design strategies, including concerns about vaccine candidates inducing infection-enhancing antibodies, are also presented.

• 日本熱帯医学会の論文
• 2011-12-01

著者

• Konishi Eiji

  Division Of Infectious Diseases Department Of International Health Kobe University Graduate School Of Health Sciences

関連論文

• Issues Related to Recent Dengue Vaccine Development
• Survey on Antibodies Specific for West Nile Virus in Horses from 2006 to 2010 in Japan
• Follow-Up Survey of Japanese Encephalitis Virus Infection in Kumamoto Prefecture, South-West Japan: Status during 2009–2011

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