Engineered biosynthesis of the antiparasitic agent frenolicin B and rationally designed analogs in a heterologous host
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概要
- 論文の詳細を見る
- 2011-12-25
著者
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Khosla Chaitan
Department Of Chemical Engineering Stanford University
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Ridley Christian
Department Of Chemistry Stanford University
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FITZGERALD Jay
Department of Chemistry, Stanford University
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Fitzgerald Jay
Department Of Chemistry Stanford University
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- Improved precursor-directed biosynthesis in E. coli via directed evolution
- Engineered biosynthesis of the antiparasitic agent frenolicin B and rationally designed analogs in a heterologous host
- In vitro and in vivo activity of frenolicin B against Plasmodium falciparum and P berghei