トリエチルホウ素と後周期遷移金属の相乗効果を利用した炭素-炭素結合形成および切断反応
スポンサーリンク
概要
- 論文の詳細を見る
Ni catalyzes homoallylation of aldehydes with 1,3-dienes in the presence of triethylborane to provide bishomoallyl alcohols. Triethylborane serves as reducing agent and Lewis acid to promote the homoallylation via oxanickelacycles. Under similar conditions, Rh catalyzes the reductive coupling reaction of aldehydes and 1,3-dienes to provide homoallyl alcohols while Pd catalyst promotes the ene-type reaction to provide dienyl homoallyl alcohols.Triethylborane also activates allylic alcohols to form π-allylpalladium key intermediates by oxidative addition of Pd(0) toward allylic C-O bonds and achieves amphiphilic allylations. A combination of Pd catalyst and triethylborane effectively promotes 3-hydroxy-4-pentenoic acid to undergo β-decarboxylative C-C bond cleavage reaction via β-vinyloxapalladacyclopentanone to provide conjugated diene and carbon dioxide.
- 社団法人 有機合成化学協会の論文
- 2012-03-01