Antibacterial effect and cytocompatibility of nano-structured TiO_2 film containing Cl
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概要
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The aim of this study was to investigate the antibacterial effect and cytocompatibility of a nano-structured TiO2 film that contained Cl and had been coated onto commercially pure titanium. First, we prepared nano-structured TiO2 by anodization with hydrofluoric acid. Then, to confer an antibacterial effect, we performed a second anodization with NaCl solutions of different concentrations (0.5 M, 1 M, 2 M). The morphology, composition, and wettability of the surface were investigated by SEM, EDS, and a video contact angle measuring system. The antibacterial effect was evaluated by film adhesion method. And cytotoxicity was determined by the viability of MG-63 cells in a MTT assay. The SEM and EDS results showed that the TiO2 nano-structure containing Cl had successfully formed after the second anodization. The contact angle analysis showed that the anodized titanium had a hydrophilic character. The results of this in vitro investigation demonstrated that the TiO2 nano-structure film anodized in 1 M NaCl had an antibacterial effect and good cell compatibility.
- 日本歯科理工学会の論文
- 2011-11-01
著者
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Kim Kyoung-nam
Department And Research Institute Of Dental Biomaterials And Bioengineering College Of Dentistry Yon
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Kim Kwang-mahn
Department Of Dental Materials Colleg Of Dentistry Yonsei University Korea Yonsei Research Institute
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Kim Kwang-mahn
Bk21 Department And Research Institute Of Dental Biomaterials And Bioengineering And Research Center For Orofacial Hard Tissue Regeneration College Of Dentistry Yonsei University
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KANG Min-Kyung
BK21, Department and Research Institute of Dental Biomaterials and Bioengineering, and Research Center for Orofacial Hard Tissue Regeneration, College of Dentistry, Yonsei University
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KANG Min-Kyung
Department and Research Institute of Dental Biomaterials and Bioengineering, and Research Center for Orofacial Hard Tissue Regeneration, College of Dentistry, Yonsei University
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MOON Seung-Kyun
Department and Research Institute of Dental Biomaterials and Bioengineering, and Research Center for Orofacial Hard Tissue Regeneration, College of Dentistry, Yonsei University
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Moon Seung-kyun
Bk21 Department And Research Institute Of Dental Biomaterials And Bioengineering And Research Center For Orofacial Hard Tissue Regeneration College Of Dentistry Yonsei University
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Kim Kwang-Mahn
Department and Research Institute of Dental Biomaterials and Bioengineering, College of Dentistry, Yonsei University, Seoul 120-752, Republic of Korea
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