Long-term Survival after Complete Mediastinal Lymph Node Resection and Lobectomy in Patients with Bulky N2 Non-small Cell Lung Cancer
スポンサーリンク
概要
- 論文の詳細を見る
Background: At Juntendo University Hospital, Japan, two patients with complete resection of bulky N2 non-small cell lung cancer (NSCLC) has survived over the long term. Therefore, we decided to retrospectively study patients who also had a complete resection of the tumor including the “bulky” superior mediastinal node for the purpose of reviewing covariates that might be related to the favorable outcome.Methods: We retrospectively analyzed the relation between covariates and survival after complete lobectomy and mediastinal lymph node resection (from April 1997 to August 2007) in 15 patients with bulky N2 NSCLC, lymph nodes greater than 2 cm in short-axis diameter (bulky nodal disease) measured on preoperative chest computer tomography. Results: Of 15 patients, 5 with bulky N2 single station had survival after the resection. Univariate analysis revealed that the postoperative stage significantly affected overall survival (p = 0.0101). Single-station node involvement in bulky N2 disease was the covariate associated with overall survival (p = 0.0150) and disease free survival (p = 0.0052). Conclusions: In the complete resection of bulky N2 NSCLC in patients with lymph nodes measuring more than 2 cm in short-axis diameter, single-station node involvement suggests a favorable outcome and long-term survival, compared to patients with multi-station involvement.
- Annals of Thoracic and Cardiovascular Surgery 編集委員会の論文
- 2011-04-01
著者
-
Suzuki Kenji
Department Of General Thoracic Surgery Juntendo University School Of Medicine
-
Inagaki Tomoya
Department Of General Thoracic Surgery Juntendo University
-
Oh Shiaki
Department Of General Thoracic Surgery Juntendo University
-
Miyasaka Yoshikazu
Department Of General Thoracic Surgery Juntendo University School Of Medicine
-
Oh Shiaki
Juntendo University School Of Medicine Department Of General Thoracic Surgery
-
Inagaki Tomoya
Juntendo University School Of Medicine Department Of General Thoracic Surgery
-
SAKURABA Motoki
Juntendo University School of Medicine, Department of General Thoracic Surgery
-
TAKAHASHI Nobumasa
Juntendo University School of Medicine, Department of General Thoracic Surgery
-
MIYASAKA Yoshikazu
Juntendo University School of Medicine, Department of General Thoracic Surgery
-
SUZUKI Kenji
Juntendo University School of Medicine, Department of General Thoracic Surgery
関連論文
- IS4-02 Safe division of pulmonary vessels/bronchus during thoracoscopic lobectomy in children under 15 kg(Respiratory System/Emergency,Share Smiles with Sick Children, Dreams and Innovation for Pediatric Surgery)
- Usefulness of suplatast tosilate for chronic cough following lung cancer surgery
- Experience of silicone gel sheets for patients with keloid scars after median sternotomy
- The Effects of Sheet-Type Absorbable Topical Collagen Hemostat Used to Prevent Pulmonary Fistula after Lung Surgery
- Resuture using Shirodkar tape for sternal dehiscence after extended thymectomy via median sternotomy
- Use of Silicone Gel Sheets for Prevention of Keloid Scars After Median Sternotomy
- The effect of one-lung ventilation upon pulmonary inflammatory responses during lung resection
- Long-term Survival after Complete Mediastinal Lymph Node Resection and Lobectomy in Patients with Bulky N2 Non-small Cell Lung Cancer
- The Cervical Anterior Approach for the Resection of Superior Posterior Neurogenic Tumor : A Case Report
- Prognosis of surgically resected lung cancer with extremely high preoperative serum carcinoembryonic antigen level