Time-Varying Nature of Risk Factors for the Longitudinal Development of Disability in Older Adults with Arthritis

スポンサーリンク

概要

• 論文の詳細を見る

• Background: To investigate changes over time in risk factors for the development of Activities of Daily Living (ADL) disabilities in older adults with arthritis.Methods: The data were obtained from the Longitudinal Survey of Health and Living Status of the Elderly in Taiwan (1989–1999). The major analytic cohort comprised 977 older adults (458 men and 519 women) with arthritis and without ADL limitation at study baseline. A generalized estimating equations (GEE) model was used to analyze all temporally correlated errors, population-averaged estimates, and longitudinal relationships.Results: Overall, the cumulative incidence of ADL disability in the analytic cohort was 17.4% during an observation period of 11 years. With respect to baseline risk, ADL disability was associated with older age, presence of comorbid chronic conditions, and poor self-rated health. However, the findings changed after accounting for the time-varying nature of risk factors and the temporal sequence of possible cause-and-effect relationships. In addition to the baseline predictors, a high score on the Center for Epidemiologic Studies Depression Scale, lack of regular exercise, and becoming widowed were associated with an increased risk of ADL disability and a decreased chance of recovery.Conclusions: An understanding of the time-varying nature of risk factors for the disabling process is essential for the development of effective interventions that aim to maintain functional ability and prevent limitations among older adults with arthritis.

• 日本疫学会の論文
• 2010-11-01

著者

• Chen Pau-chung

  Institute Of Occupational Medicine And Industrial Hygiene Collage Of Public Health National Taiwan U

• Lin Kuan-chia

  School Of Nursing National Taipei University Of Nursing And Health Sciences

• Lee Hui-lan

  School Of Nursing National Taipei University Of Nursing And Health Sciences

• Chi Lin-yang

  Department Of Dentistry National Yang-ming University

• TWISK J.

  Department of Epidemiology and Biostatistics, VU Medical Centre, Amsterdam and Department of Health

• Twisk J.

  Department Of Epidemiology And Biostatistics Vu Medical Centre Amsterdam And Department Of Health Sc

• Chen Pau-chung

  Institute Of Occupational Medicine And Industrial Hygiene College Of Public Health National Taiwan U

関連論文

• Increased Risk of Hospitalization Related to Motor Vehicle Accidents Among People Taking Zolpidem: A Case–Crossover Study
• Increased Mortality Risk for Cancers of the Kidney and Other Urinary Organs among Chinese Herbalists
• Analysis of perfluorinated chemicals in umbilical cord blood by ultra-high performance liquid chromatography/tandem mass spectrometry
• Time-Varying Nature of Risk Factors for the Longitudinal Development of Disability in Older Adults with Arthritis
• Increased Risk of Hospitalization Related to Motor Vehicle Accidents Among People Taking Zolpidem : A Case-Crossover Study
• Lifetime Residential Mobility History and Self-Rated Health at Midlife
• Longitudinal Impact of Frequent Geographic Relocation from Adolescence to Adulthood on Psychosocial Stress and Vital Exhaustion at Ages 32 and 42 Years: The Amsterdam Growth and Health Longitudinal Study
• Longitudinal Impact of Frequent Geographic Relocation from Adolescence to Adulthood on Psychosocial Stress and Vital Exhaustion at Ages 32 and 42 Years : The Amsterdam Growth and Health Longitudinal Study

スポンサーリンク