Investigation of degradation processes in IgG1 monoclonal antibodies by limited proteolysis coupled with weak cation-exchange HPLC
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概要
- 論文の詳細を見る
- 2010-04-01
著者
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LAU Hollis
Department of Analytical & Formulation Sciences
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LATYPOV Ramil
Department of Analytical & Formulation Sciences
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Lau Hollis
Department Of Analytical & Formulation Sciences Amgen Inc.
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Latypov Ramil
Department Of Analytical & Formulation Sciences Amgen Inc.
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Mcgrath Theresa
Department Of Process Development Amgen Inc.
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Yan Boxu
Department Of Analytical & Formulation Sciences Amgen Inc.
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PACE Danielle
Department of Analytical & Formulation Sciences, Amgen Inc.
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SMALLWOOD Scott
Department of Cell Science and Technology, Amgen Inc.
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PATEL Ketaki
Department of Formulation and Analytical Resources, Amgen Inc.
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PARK Jihea
Department of Formulation and Analytical Resources, Amgen Inc.
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PARK SungAe
Department of Formulation and Analytical Resources, Amgen Inc.
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Patel Ketaki
Department Of Formulation And Analytical Resources Amgen Inc.
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Park Jihea
Department Of Formulation And Analytical Resources Amgen Inc.
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Pace Danielle
Department Of Analytical & Formulation Sciences Amgen Inc.
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Smallwood Scott
Department Of Cell Science And Technology Amgen Inc.
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Park Sungae
Department Of Formulation And Analytical Resources Amgen Inc.
関連論文
- Analysis of human antibody IgG2 domains by reversed-phase liquid chromatography and mass spectrometry
- Characterization of a unique IgG1 mAb CEX profile by limited Lys-C proteolysis/CEX separation coupled with mass spectrometry and structural analysis
- Investigation of degradation processes in IgG1 monoclonal antibodies by limited proteolysis coupled with weak cation-exchange HPLC