Genetic Interaction between Ribosome Biogenesis and Inositol Polyphosphate Metabolism in Saccharomyces cerevisiae
スポンサーリンク
概要
- 論文の詳細を見る
Rrs1 has an essential role in 60S ribosomal subunit assembly in Saccharomyces cerevisiae. We isolated a temperature-sensitive kcs1 mutant that suppresses the cold sensitivity of rrs1-1. The kcs1 allele, resulting in truncation of inositol 6 phosphate kinase domain, and kcs1 disruption suppress a defect of rrs1-1 in 60S ribosomal subunit assembly. These results suggest that inositol polyphosphate metabolism affects ribosome biogenesis in yeast.
- 2009-02-23
著者
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HORIGOME Chihiro
Department of Biofunctional Science and Technology, Graduate School of Biosphere Science, Hiroshima
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MIZUTA Keiko
Department of Biofunctional Science and Technology, Graduate School of Biosphere Science, Hiroshima
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Ikeda Ryo
Department Of Biofunctional Science And Technology Graduate School Of Biosphere Science Hiroshima Un
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Okada Takafumi
Department Of Biofunctional Science And Technology Graduate School Of Biosphere Science Hiroshima Un
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TAKENAMI Kazuhiko
Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima Uni
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Horigome Chihiro
Department Of Biofunctional Science And Technology Graduate School Of Biosphere Science Hiroshima Un
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Takenami Kazuhiko
Department Of Molecular Biotechnology Graduate School Of Advanced Sciences Of Matter Hiroshima Unive
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Mizuta Keiko
Department Of Biofunctional Science And Technology Graduate School Of Biosphere Science Hiroshima Un
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