Structural Analysis of a Bioactive Polysaccharide, PISP1, from the Medicinal Mushroom Phellinus igniarius

スポンサーリンク

概要

• 論文の詳細を見る

• PISP1, a heteropolysaccharide isolated from fruiting bodies of Phellinus igniarius by hot aqueous extraction and purified by DEAE-Sepharose anion-exchange and gel filtration chromatography, is composed of fucose, galactose, mannose, and 3-O-Me-galactose in a ratio of 1:2:1:2. Methylation, monosaccharide analysis, and NMR studies (1H NMR, 13C NMR, COSY-45°, TOCSY, ROESY, HSQC, and HMBC) revealed that PISP1 had a backbone consisting of 1,6-disubstituted-3-O-Me-α-D-galactopyranosyl residue, 1,3,6-trisubstituted-α-D-manopyranosyl residue, 1,4-disubstituted-α-D-galactopyranosyl residue, and 1,2-disubstituted-α-D-galactopyranosyl residue, and had a 1-substituted-α-L-fucopyranosyl terminal attached to O-3 of a manopyranosyl residue. Preliminary bioactivity tests conducted in vitro revealed that PISP1 stimulated the proliferation of mouse spleen lymphocytes.

• 社団法人 日本農芸化学会の論文
• 2009-01-23

著者

• Yang Yan

  Institute Of Edible Fungi Shanghai Academy Of Agricultural Sciences

• TANG Qingjiu

  Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences

• YE LiBin

  College of Food Science and Biotechnology, Zhejiang Gongshang University, Food Safety Key Lab of Zhe

• ZHANG JingSong

  Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences

• LIU YanFang

  Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences

• Liu Yanfang

  Institute Of Edible Fungi Shanghai Academy Of Agricultural Sciences

• Ye Libin

  College Of Food Science And Biotechnology Zhejiang Gongshang University Food Safety Key Lab Of Zheji

• Tang Qingjiu

  Inst. Of Edible Fungi Shanghai Acad. Of Agricultural Sciences

• Tang Qingjiu

  Institute Of Edible Fungi Shanghai Academy Of Agricultural Sciences

• Zhang Jingsong

  Institute Of Edible Fungi Shanghai Academy Of Agricultural Sciences

関連論文

• Effects of Osthole on Migration and Invasion in Breast Cancer Cells
• Structural Analysis of a Bioactive Polysaccharide, PISP1, from the Medicinal Mushroom Phellinus igniarius

スポンサーリンク