Accelerated Chronological Aging of a Mutant Fission Yeast Deficient in Both Glutathione and Superoxide Dismutase Having Cu and Zn as Cofactors and Its Enhancement by Sir2 Deficiency
スポンサーリンク
概要
- 論文の詳細を見る
A mutant of Schizosaccharomyces pombe deficient in both superoxide dismutase with copper and zinc as cofactors and glutathione was hypersensitive to menadione, which intracellularly generates superoxide radicals, and showed short chronological lifespan with more oxidation of proteins. Disruption of the sir2 gene in the double mutant enhanced the short chronological lifespan without more enhanced protein oxidation.
- 社団法人 日本農芸化学会の論文
- 2007-11-23
著者
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Mutoh Norihiro
Department Of Genetics Institute For Developmental Research
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Kitajima Satoko
Department Of Genetics Institute For Developmental Research Aichi Human Service Center
関連論文
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- Two Distinct Upstream Regions Are Involved in Expression of the Catalase Gene in Schizosaccharomyces pombe in Response to Oxidative Stress
- CHANGES OF CALMODULIN AND S-100 PROTEIN IN C6 GLIOMA CELLS AS A RESULT OF CELLULAR DIFFERENTIATION INDUCED BY FORSKOLIN
- Apoptotic Cell Death in the Fission Yeast Schizosaccharomyces pombe Induced by Valproic Acid and Its Extreme Susceptibility to pH Change
- Accelerated Chronological Aging of a Mutant Fission Yeast Deficient in Both Glutathione and Superoxide Dismutase Having Cu and Zn as Cofactors and Its Enhancement by Sir2 Deficiency
- Effects of Four Oxidants, Menadione, 1-Chloro-2,4-Dinitrobenzene, Hydrogen Peroxide and Cumene Hydroperoxide, on Fission Yeast Schizosaccharmoyces pombe
- Transcriptional Regulation of Catalase Gene in the Fission Yeast Schizosaccharomyces pombe: Molecular Cloning of the Catalase Gene and Northern Blot Analyses of the Transcript
- Molecular Cloning and Nucleotide Sequencing of the γ-Glutamylcysteine Synthetase Gene of the Fission Yeast Schizosaccharomyces pombe
- Apoptotic Cell Death in the Fission Yeast Schizosaccharomyces pombe Induced by Valproic Acid and Its Extreme Susceptibility to pH Change