Influence of Dynamic Training on Hemodynamic, Neurohormonal Responses to Static Exercise and on Inflammatory Markers in Patients After Coronary Artery Bypass Grafting

スポンサーリンク

概要

• 論文の詳細を見る

• Background:  Little is known about the influence of dynamic training on the hemodynamic and neurohormonal responses to static exercise and on inflammatory markers in optimally treated post-coronary artery bypass grafting (CABG) patients. Methods and Results:  One hundred and twenty male patients, aged 55±6 years, 3 months after receiving CABG, were randomized to either 6 weeks of aerobic training on a cycloergometer, 3 times a week, at a 70-80% of the maximum tolerated heart rate (HR) (training group, n=60) or to a control group (n=60). At baseline and at the end of the study, all patients underwent: (1) a cardiopulmonary test; (2) handgrip at 30% of maximal voluntary contraction for 3min in a sitting position during in which HR, blood pressure (BP), stroke volume (SV, by impedance cardiography), cardiac output (CO) and total peripheral resistance (TPR) were monitored; and (3) plasma level assessment of catecholamines, nitric oxide and inflammatory markers. During the final tests, handgrip-induced increases in HR, BP, and TPR (14% vs 27%, P<0.01) were lower, whereas SV and CO were higher (by 13% and 15%, respectively, P<0.05) in trained patients compared with controls. Moreover, a higher increase in nitric oxide level (46% vs 14%, P<0.01) and a lower increase in noradrenaline (11% vs 20%, P<0.05) were observed in trained patients compared with controls. Accordingly, training caused significant improvement in peak oxygen uptake per kilogram body weight (peak VO2) and inflammatory markers. Conclusions:  Short-term dynamic training caused significant improvement of hemodynamic and neurohormonal responses to handgrip, cardiovascular fitness and inflammatory state. (Circ J 2010; 74: 2598-2604)

• 社団法人　日本循環器学会の論文
• 2010-11-25

著者

• Bilinska Maria

  Department Of Cardiac Rehabilitation And Noninvasive Electrocardiology Institute Of Cardiology

• KOSYDAR-PIECHNA Magdalena

  Department of Cardiac Rehabilitation and Noninvasive Electrocardiology, Institute of Cardiology

• GASIOROWSKA Anna

  Department of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences

• MIKULSKI Tomasz

  Department of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences

• PIOTROWSKI Walerian

  Department of Epidemiology, Cardiovascular Disease Prevention and Health Promotion, Institute of Car

• NAZAR Krystyna

  Department of Applied Physiology, Mossakowski Medical Research Centre, Polish Academy of Sciences

• PIOTROWICZ Ryszard

  Department of Cardiac Rehabilitation and Noninvasive Electrocardiology, Institute of Cardiology

• Nazar Krystyna

  Department Of Applied Physiology Mossakowski Medical Research Centre Polish Academy Of Sciences

• Mikulski Tomasz

  Department Of Applied Physiology Mossakowski Medical Research Centre Polish Academy Of Sciences

• Gasiorowska Anna

  Department Of Applied Physiology Mossakowski Medical Research Centre Polish Academy Of Sciences

• Piotrowicz Ryszard

  Department Of Cardiac Rehabilitation And Noninvasive Electrocardiology Institute Of Cardiology

• Piotrowski Walerian

  Department Of Epidemiology Cardiovascular Disease Prevention And Health Promotion Institute Of Cardi

• Kosydar-piechna Magdalena

  Department Of Cardiac Rehabilitation And Noninvasive Electrocardiology Institute Of Cardiology

関連論文

• Influence of Dynamic Training on Hemodynamic, Neurohormonal Responses to Static Exercise and on Inflammatory Markers in Patients After Coronary Artery Bypass Grafting
• Exercise Is Beneficial : But How and Why?
• Exercise Is Beneficial: But How and Why?:– Reply –

スポンサーリンク