An in Vitro Evaluation Method to Test Ocular Irritation using a Human Corneal Epithelium Model

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概要

• 論文の詳細を見る
• 2008-10-31

著者

• KATOH Masakazu

  Japan Tissue Engineering Co., Ltd., R&D Department

• KOJIMA Hajime

  Japanese Center for the Validation of Alternative Methods (JaCVAM), National Institute of Health Sci

• Katoh Masakazu

  Japan Tissue Engineering Co. Ltd.

• ARAI Shoko

  Japanese Center for the Validation of Alternative Methods(JaCVAM), National Institute of Health Scie

• YAMAMOTO Naoki

  Fujita Health University

• Arai Shoko

  食品薬品安全センター

• Kojima Hajime

  Japanese Center For The Validation Of Alternative Methods(jacvam) National Institute Of Health Scien

• Kojima Hajime

  Japanese Center For The Validation Of Alternative Methods (jacvam) National Institute Of Health Scie

• Arai Shoko

  Japanese Center For The Validation Of Alternative Methods(jacvam) National Institute Of Health Scien

関連論文

• Assessment of the human epidermal model LabCyte EPI-MODEL for In vitro skin corrosion testing according to the OECD test guideline 431
• Validation of human skin models for skin corrosivity tests in Japan
• An in Vitro Evaluation Method to Test Ocular Irritation using a Human Corneal Epithelium Model
• "C-5 Validation of alternatives to eye irritation tests for cosmetic ingredients (Results of the first, second, and third validation).
• THE SECOND PHASE VALIDATION STUDY OF ALTERNATIVE METHODS TO THE EYE IRRITATION TEST FOR COSMETIC INGREDIENTS 10)EVALUATION OF CYTOTOXICITY TEST ON CHL CELLS
• THE SECOND PHASE VALIDATION STUDY OF ALTERNATIVE METHOD TO THE EYE IRRITATION TEST 8.Evaluation of Cytotoxicity Test in SIRC Cells
• The second phase validation study of alternative methods to the eye irritation test (4) Evaluation of hemoglobin denaturation tests.
• The second phase validation study of alternative methods to the eye irritation test : Evaluation of Skin-squared ZK1100 and ZK1200 Models
• THE SECOND PHASE OF VALIDATION STUDY OF ALTERNATIVE METHODS TO THE EYE IRRITATION TEST FOR COSMETIC INGREDIENTS 7) EVALUATION OF CYTOTOXICITY TESTS WITH Cornepack
• The second phase validation study of alternative methods to the eye irritation test (6)Evaluation of MATREX ^
• The second phase validation study of alternative methods to the eye irritation test for cosmetic ingredients 3) Evaluation of Hemolysis test.
• The second phase validation study of alternative methods to the eye irritation test (2) Evaluation of chorioallantoic membrane (CAM) tests.
• Validation of alternative methods to eye irritaion test for safety evaluation of cosmetic ingredients, project and progress.
• Commentary to the Discussion on Topic 3, "In Vitro Test Approaches with Better Predictivity" at the 5th International Workshop on Genotoxicity Testing (IWGT)
• The Skin Irritation Test using the Human Epidermal Model LabCyte EPI-MODEL24 : examination with 54 materials
• Reproducibility of human 3-dimensional cultured epidermal model (LabCyte EPI-MODEL)
• Investigation of the Test Method for Eye Irritation potential Using a Reconstructed Human Corneal Model
• Functional evaluation of human 3-dimensional keratinocyte and melanocyte co-cultured epidermal model (LabCyte MELANO-MODEL)
• Assessment of the Human Epidermal Model LabCyte EPI-MODEL24 for the in vitro Skin Irritation Testing according to the validated protocol by ECVAM
• Investigation of 3D corneal model culture method using normal human corneal epithelial cells
• Skin irritant tests using human 3-dimensional cultured epidermal model (LabCyte EPI-MODEL) : Analysis by inflammatory cytokines
• The morphological and functional study of human 3-dimensional cultured epidermal model (LabCyte EPI-MODEL) : Evaluation of proliferation, differentiation and secreted cytokines
• Reproducibility of human 3-dimensional cultured epidermal model (LabCyte EPI-MODEL) for an alternative to animal testing

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