Long-Term Clinical Outcome After Endovascular Treatment in Patients With Intermittent Claudication due to Iliofemoral Artery Disease

概要

論文の詳細を見る
Background: The natural history of patients with intermittent claudication (IC) has been reported, but little is known about that of claudicant patients after endovascular therapy (EVT). Methods and Results: A total of 271 consecutive patients (mean age, 68±6 years, 82% men) with IC were treated with EVT for a de novo iliofemoral lesion. Primary patency was defined as treated vessel without re-stenosis and repeat revascularization. Major adverse cardiovascular event (MACE) included death, myocardial infarction and stroke. Median follow-up interval was 11.7±2.9 years. During the follow-up period, 132 patients died (cardiovascular death; 66%). Major amputation was performed in 4 patients. Primary patency rate was 82%, 79%, and 78% at 5, 10 and 15 years, respectively. Freedom from all-cause death (MACE) was 73% (69%), 58% (49%), and 43% (34%) at 5, 10 and 15 years. On multivariate Cox regression, Trans-Atlantic Inter-society Consensus grade C/D, and involvement of femoropopliteal lesion were independent predictors of primary patency. Independent predictors for overall survival were age, left ventricular dysfunction (ejection fraction <40%), coronary artery disease, diabetes, chronic kidney disease and below-the-knee disease. Conclusions: Regardless of good clinical patency of treated vessel in patients with IC, survival was poor. Independent predictors were different between long-term patency and late mortality. (Circ J 2010; 74: 1689 - 1695)
社団法人　日本循環器学会の論文
2010-07-25

Long-Term Clinical Outcome After Endovascular Treatment in Patients With Intermittent Claudication due to Iliofemoral Artery Disease

スポンサーリンク

概要

著者

関連論文

スポンサーリンク