Rheumatoid Arthritis : A Model of Systemic Inflammation Driving Atherosclerosis

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概要

• 論文の詳細を見る

• Similarities between the inflammatory pathways in atherosclerosis and rheumatoid arthritis (RA) are striking. Chronic systemic inflammation in RA patients leads to cardiovascular (CV) events beyond traditional cardiac risk factors. Clinicians typically focus on treating the joint manifestations of RA while neglecting to eliminate systemic inflammation, which leaves RA patients vulnerable to adverse CV events. In this review we provide an understanding of how systemic inflammation in RA accelerates atherosclerosis. This knowledge should guide therapeutic targets to minimize CV risk in RA, and may lead to insights into the inflammatory mechanisms of atherosclerosis in general. (Circ J 2009; 73: 977-985)

• 社団法人　日本循環器学会の論文
• 2009-05-20

著者

• Ganz Peter

  Division Of Cardiology And The Center Of Excellence In Vascular Research San Francisco General Hospi

• KU Ivy

  Division of Cardiology and the Center of Excellence in Vascular Research, San Francisco General Hosp

• IMBODEN John

  Division of Rheumatology, San Francisco General Hospital, University of California

• HSUE Priscilla

  Division of Cardiology and the Center of Excellence in Vascular Research, San Francisco General Hosp

• Imboden John

  Division Of Rheumatology San Francisco General Hospital University Of California

• Ku Ivy

  Division Of Cardiology And The Center Of Excellence In Vascular Research San Francisco General Hospi

• Hsue Priscilla

  Division Of Cardiology And The Center Of Excellence In Vascular Research San Francisco General Hospi

関連論文

• Rheumatoid Arthritis : A Model of Systemic Inflammation Driving Atherosclerosis

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