Development and validation of an enantioselective HPLC-UV method using Chiralpak AD-H to quantify (+)- and (-)-torcetrapib enantiomers in hamster plasma-application to a pharmacokinetic study

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概要

• 論文の詳細を見る
• 2007-10-01

著者

• Dubey P.

  Department Of Chemistry Jntu College Of Engineering

• Mullangi Ramesh

  Drug Metabolism And Pharmacokinetics Discovery Research Dr. Reddy's Laboratories Ltd.

• Srinivas Nuggehally

  Drug Metabolism And Pharmacokinetics Discovery Research Dr. Reddy's Laboratories Ltd.

• Trivedi Ravi

  Drug Metabolism And Pharmacokinetics Discovery Research Dr. Reddy's Laboratories Ltd.

• MULLANGI Ramesh

  Drug Metabolism and Pharmacokinetics, Discovery Research, Dr. Reddy's Laboratories Ltd.

関連論文

• Development and validation of a chiral liquid chromatographic method, based on Chiralpak^【○!R】 to quantify enantiomers of (±)-DRF 2725 in rat plasma : lack of inversion of ragaglitazar (S(-)-DRF 2725) to its antipode in plasma
• Concurrent determination of ezetimibe and its phase-I and II metabolites by HPLC with UV detection : Quantitative application to various in vitro metabolic stability studies and for qualitative estimation in bile
• Chiral bioanalysis of torcetrapib enantiomers in hamster plasma by normal-phase liquid chromatography and detection by atmospheric pressure chemical ionization tandem mass spectrometry
• Development and validation of an enantioselective HPLC-UV method using Chiralpak AD-H to quantify (+)- and (-)-torcetrapib enantiomers in hamster plasma-application to a pharmacokinetic study
• High Field Transport Phenomena in n-InSb at High Temperatures

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