Mycotoxin Toxicity in Saccharomyces cerevisiae Differs Depending on Gene Mutations
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概要
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Mycotoxin inhibits the growth of Saccharomyces cerevisiae mutants with disrupted stress response genes, but no that of wild type yeast even at high concentrations. The S. cerevisiae genome database (SGD) project has recently generated many gene disruptants, including those with disrupted stress responseassociated genes. The present study examined the relationship between mycotoxicity and the disruption of functional yeast genes, especially those involved with stress responses. Growth tests showed a major impact in strains other than those with disrupted stress response genes as well as mycotoxin susceptibility of several strains by sodium dodecyl sulfate.
- 2009-07-01
著者
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SUZUKI Tadahiro
Applied Microbiology Division, National Food Research Institute
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SIRISATTHA Sophon
Health Technology Research Center, National Institute of Advanced Industrial Science and Technology
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MORI Katsumi
Applied Microbiology Division, National Food Research Institute
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IWAHASHI Yumiko
Applied Microbiology Division, National Food Research Institute
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Sirisattha Sophon
National Inst. Of Advanced Industrial Sci. And Technol. (aist) Ibaraki Jpn
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Sirisattha Sophon
Health Technology Research Center National Institute Of Advanced Industrial Science And Technology (
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Iwahashi Yumiko
Applied Microbiology Division National Food Research Institute
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Suzuki Tadahiro
National Food Res. Inst. Ibaraki Jpn
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Suzuki Tadahiro
Applied Microbiology Division National Food Research Institute
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Mori Katsumi
Applied Microbiology Division National Food Research Institute
関連論文
- Mycotoxin Toxicity in Saccharomyces cerevisiae Differs Depending on Gene Mutations
- New Method for the Assessment of Biological Effect by Surfactants Using Yeast DNA Microarray