Simultaneous determination of NK-104 and its lactone in biological samples by column-switching high-performance liquid chromatography with ultraviolet detection

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概要

• 論文の詳細を見る
• 1999-03-05

著者

• KANDA Hiroyasu

  日産化学工業株式会社中央研究所

• KIMATA Hideki

  興和株式会社東京研究所

• Kimata H

  Kowa Company Ltd. Tokyo

• Kojima Juniji

  興和株式会社東京研究所

• Kojima Junji

  Tokyo New Drug Research Laboratories Kowa Company Ltd.

• Kojima Junji

  Ntt Human Interface Laboratories

• Fujino Hideki

  Tokyo New Drug Research Laboratories Kowa Company Ltd.

• KIMATA Hideki

  Tokyo Research Laboratories, Kowa Co., Ltd.

• YOSIMURA Mitsuo

  Tokyo Research Laboratories, Kowa Company Ltd.

• MORIKAWA Hiroaki

  Hino Laboratory, Teijin Bio Laboratories Inc.

• Yosimura Mitsuo

  Tokyo Research Laboratories Kowa Company Ltd.

• Morikawa Hiroaki

  Hino Laboratory Teijin Bio Laboratories Inc.

• Kimata Hideki

  Tokyo Research Laboratories, Kowa Co. Ltd.

関連論文

• Studies on the Metabolic Fate of NK-104, a New Inhibitor of HMG-CoA Reductase (4) : Interspecies Variation in Laboratory Animals and Humans
• Importance of Sialic Acid in Recombinant Thrombomodulin in Terms of Pharmacokinetics and Separation of Desialyzed Glycoprotein
• Binding of Human Tissue Plasminogen Activator (t-PA) to Blood Clots and Clot-Lytic Activity of Clot-Bound t-PA
• Effect of Biliary Excretion on the Pharmacokinetics of Pitavastatin (NK-104) in Dogs
• Uptake Mechanism of Pitavastatin, a New Inhibitor of HMG-CoA Reductase, in Rat Hepatocytes
• Metabolic Fate of Pitavastatin, a New Inhibitor of HMG-CoA Reductase : Effect of cMOAT Deficiency on Hepatobiliary Excretion in Rats and of mdr1a/b Gene Disruption on Tissue Distribution in Mice
• Studies on the Metabolic Fate of NK-104, a New Inhibitor of HMG-CoA Reduetase (5) : In Vitro Metabolism and Plasma Protein Binding in Animals and Human
• Simultaneous determination of NK-104 and its lactone in biological samples by column-switching high-performance liquid chromatography with ultraviolet detection
• Identification of Metabolites of NK-104,an HMG-CoA Reductase Inhibitor, in Rat, Rabbit and Dog Bile
• A Fast Projection Algorithm for Adaptive Filtering
• Studies on the Metabolic Fate of NK-104, a New Inhibitor of HMG-CoA Reductase (2) : Absorption, Distribution, Metabolism, Excretion and Accumulation Following Repeated Oral Administration of ^C-NK-104 in Rats
• Studies on the Metabolic Fate of NK-104, a New Inhibitor of HMG-CoA Reductase (1) : Absorption, Distribution, Metabolism and Excretion in Rats
• Thrombolytic Effect of Tissue Plasminogen Activator in a Cerebral Embolic Model
• Localization of Tissue Plasminogen Activator on Experimental Microthrombi in Rats. Microautoradiographic Observations
• Localization of Tissue Plasminogen Activator on Experimental Thrombi in Rats
• PHARMACOKINETICS OF NIPRADILOL (K-351), A NEW ANTIHYPERTENSIVE AGENT. I. STUDIES ON INTERSPECIES VARIATION IN LABORATORY ANIMALS
• PHARMACOKINETICS OF NIPRADILOL (K-351), A NEW ANTIHYPERTENSIVE AGENT. II. INFLUENCE OF THE ROUTE OF ADMINISTRATION ON BIOAVAILABILITY IN DOGS
• Studies on metabolic fate of pitavastatin (NK-104), a new inhibitor of HMG-CoA reductase-Does glucronidation mediate the lactonization of pitavastatin?
• Simultaneous determination of taxol and its metabolites in microsomal samples by a simple thin-layer chromatography radioactivity assay-inhibitory effect of NK-104, a new inhibitor of HMG-CoA reductase
• Studies on the Metabolic Fate of NK-104, a New Inhibitor of HMG-CoA Reductase (3) : Foeto-placental Transfer and Mammary Excretion after Oral Administration in Rats
• Pharmacokinetics of nipradilol (K-351), a new antihypertensive agent, in human.
• Possibility of the Low Defensive Fibrinolysis in SHRSP

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