The Effect of Microfluidic Geometry for in situ Generating Monodispersed Hydrogels

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概要

• 論文の詳細を見る

• The geometric effect of microfluidic channels on the production of monodispersed alginate hydrogels was investigated. The general flow focusing design could not produce stable hydrogels because the synthesis between alginate and calcium chloride at the junction strongly depends on the diffusion limited reaction. The addition of winding microchannels as a mixing line could not perfectly solve the diffusion problem because imperfect mixing of alginate and calcium solutions results in unstable generation of alginate microbeads and merging of the produced alginate beads in the microfluidic devices. The last microfluidic design adopted a mechanism in which the droplet formation was based on a biased shear-force-driven break-off to improve rapid droplet formation and mixing efficiency. The final design of microfluidic device could promptly produce the stable monodispersed-hydrogel beads.

• 社団法人 化学工学会の論文
• 2008-07-01

著者

• Jung Jae-hoon

  Department Of Chemical Engineering Chungnam National University

• LEE Chang-Soo

  Department of Applied Biochemistry, Division of Life Science, College of Biomedical and Health Scien

• Lee Chang-soo

  Department Of Applied Biochemistry Division Of Life Science College Of Biomedical And Health Science

• Lee Chang-soo

  Department Of Chemical Engineering Chungnam National University

• Kim Dong-pyo

  Department Of Applied Chemistry Chungnam National University

• CHOI Chang-Hyung

  Department of Chemical Engineering, Chungnam National University

• YOON Tae-Ho

  Department of Applied Chemistry, Chungnam National University

• Yoon Tae-ho

  Department Of Applied Chemistry Chungnam National University

• Choi Chang-hyung

  Department Of Chemical Engineering Chungnam National University

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