Amino Acid Mixture Identical to Vespa Larval Saliva Increases both Leptin Secretion and Basal Lipolysis in Rat Adipocytes
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概要
- 論文の詳細を見る
The effect of vespa amino acid mixture solution (VAAM), a unique amino acid mixture identified in the saliva of the larva of a species of hornet endemic to Japan on adipocyte lipolysis was investigated in order to verify the possible mechanisms underlying the regulatory effect of VAAM on in vivo fat metabolism. VAAM significantly increased basal leptin secretion and lipolysis without an increase in cAMP production. However, VAAM failed to amplify either isoproterenol or dibutylyl cAMP-stimulated lipolysis, which is increased intracellular cAMP productions, accompanied by a significant decrease in leptin secretion. These results suggest that VAAM may enhance basal lipolysis independent of cAMP productions, but is dependant on leptin secretion from adipocytes themselves, at least in part.
- 2008-01-01
著者
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OGASAWARA Junetsu
Center for Intellectual Property Strategies, Sponsored Laboratory, The Institute of Physical and Che
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ABE Takashi
Center for Intellectual Property Strategies, Sponsored Laboratory, The Institute of Physical and Che
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Ogasawara Junetsu
Center For Intellectual Property Strategies Sponsored Laboratory The Institute Of Physical And Chemi
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Abe Takashi
Center For Information Biology And Dna Data Bank Of Japan National Institute Of Genetics And The Gra
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Abe Takashi
Center For Intellectual Property Strategies Sponsored Laboratory The Institute Of Physical And Chemi
関連論文
- Amino Acid Mixture Identical to Vespa Larval Saliva Increases both Leptin Secretion and Basal Lipolysis in Rat Adipocytes
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