Total Syntheses of FR901464

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概要

• 論文の詳細を見る

• Three total syntheses of potent anticancer natural product FR901464 are described. The first total synthesis by the Jacobsen group used transition metal-catalyzed reactions to prepare their chiral fragments. Subsequently, the Kitahara group described their synthesis using the chiral pool to construct their building blocks. Finally, the Koide group published the most recent synthesis of FR901464 using both asymmetric reactions and the chiral pool for their chiral fragment syntheses. It is envisioned that these total syntheses will assist biological studies of FR901464 and its unique mode of action.

• 社団法人 有機合成化学協会の論文
• 2007-02-01

著者

• Koide Kazunori

  Department Of Chemistry University Of Pittsburgh

• ALBERT Brian

  Department of Chemistry, University of Pittsburgh

• Albert Brian

  Department Of Chemistry University Of Pittsburgh

• 小出 和則

  Department of Chemistry, University of Pittsburgh

関連論文

• Total Syntheses of FR901464

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