White Matter Changes in Elderly People : MR-pathologic Correlations
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概要
- 論文の詳細を見る
Magnetic resonance (MR) imaging features of white matter lesions, often seen in the elderly, are correlated with histologic findings. Dilatation of perivascular spaces is seen, especially in the frontal and/or parietal subcortical white matter; the spaces are less than 3 mm in diameter and have sharp margins with no perifocal abnormality. Old lacunar infarcts are larger than 3 mm in diameter and are irregularly shaped and accompanied by perifocal myelin pallor and gliosis. Periventricular hyperintensity, including cap and rim, histologically shows myelin pallor, dilatation of perivascular spaces, discontinuity of the ependymal lining, and subependymal gliosis. Deep and subcortical white matter hyperintensity reflects myelin pallor and dilatation of perivascular spaces. Diffuse white matter lesion, seen in Binswangers disease, shows myelin pallor and tissue rarefaction associated with loss of myelin and axons. U-fibers are usually well preserved. Severe arteriosclerosis and arteriolosclerosis are usually seen in the white matter. Knowledge of the pathologic features of incidental changes in white matter helps in understanding MR imaging findings.
- 日本磁気共鳴医学会の論文
- 2006-07-10
著者
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Fujii Shinya
Division Of Radiology Department Of Pathophysiological And Therapeutic Science Faculty Of Medicine T
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KINOSHITA Toshibumi
Department of Radiology and Nuclear Medicine, Akita Research Institute of Brain and Blood Vessels
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Fujii Shinya
Division Of Cardiology Saitama Prefecture Cardiovascular And Respiratory Center
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OGAWA Toshihide
Division of Radiology, Faculty of Medicine, Tottori University
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MATSUSUE Eiji
Division of Radiology, Department of Pathophysiological and Therapeutic Science
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SUGIHARA Shuji
Division of Radiology, Department of Pathophysiological and Therapeutic Science
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OHAMA Eisaku
Department of Neuropathology, Institute of Neurological Sciences, Faculty of Medicine, Tottori Unive
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Kinoshita Toshibumi
Division Of Radiology Department Of Pathophysiological And Therapeutic Science Faculty Of Medicine T
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Kinoshita Toshibumi
Department Of Radiology And Nuclear Medicine Akita Research Institute Of Brain And Blood Vessels
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Ohama Eisaku
Department Of Neuropathology Institute Of Neurological Sciences Faculty Of Medicine Tottori Universi
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Ohama Eisaku
Department Of Neuropathology Institute Of Neurological Sciences
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Matsusue Eiji
Division Of Radiology Department Of Pathophysiological And Therapeutic Science
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Sugihara S
Tottori Univ. Yonago Jpn
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Sugihara Shuji
Division Of Radiology Department Of Pathophysiological And Therapeutic Science
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Ogawa Toshihide
Division Of Radiology Department Of Pathophysiological And Therapeutic Science Faculty Of Medicine T
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Ogawa Toshihide
Division Of Radiology Department Of Pathophysiological And Therapeutic Science Faculty Of Medicine T
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Fujii Shinya
Division Of Cardiology Department Of Internal Medicine The Jikei University School Of Medicine
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Kinoshita Toshibumi
Department Of Radiology Akita Research Institute For Brain And Blood Vessels
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