Effects of Dietary Genistein on Nutrient Use and Mineral Status in Heat-Stressed Quails

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概要

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• Genistein is a powerful antioxidant and plays a role in calcium and bone metabolism. We evaluated the efficacy of dietary supplementation with genistein on the nutrient use and mineral concentrations in tibia and serum of quails reared at high environmental temperature (34°C). Two hundred and forty Japanese quails (10 days old) were randomly assigned to 8 treatment groups consisting of 10 replicates of 3 birds. The birds were kept in a temperature-controlled room at 22°C (Thermoneutral, TN groups) or 34°C (for 8 h/d; 09.00 am-05.00 pm; Heat stress, HS groups). Birds were fed either a basal diet (TN and HS) or the basal diet supplemented with 200, 400 or 800 mg of genistein/kg of diet. Heat exposure decreased apparent nutrient digestibility and bone mineralization when the basal diet was fed (P<0.001). Apparent digestibility of dry matter (DM) (P<0.05), crude protein (CP) (P<0.05) and ash (P<0.01) was significantly improved by genistein supplementation. However, this improvement was not in direct proportion to increased doses of supplement since there was no difference when diets included either 400 or 800 mg genistein/kg of diet (P<0.05) in birds reared under heat stress. The amounts of Ca, P, Mg, Mn, Zn, Fe and Cu in the excreta decreased (P<0.01), while Ca, P, Mg, Mn, Zn and Cu concentrations in tibia ash increased in quails reared under heat stress conditions (P<0.01) with genistein supplementation. Ca and P concentrations in tibia ash were also increased in birds kept under thermoneutral conditions with genistein supplementation. Increased serum alkaline phosphatase activity (P<0.01) was associated with increasing dietary genistein in all groups. In conclusion, genistein supplementation to the basal diet improved digestibility of CP, DM and ash and levels of Ca and P and bone mineralization in quails reared under heat stress conditions.

• 2006-04-01

著者

• Sarkar Fazlul

  Karmanos Cancer Institute Wayne State University

• DOERGE Daniel

  National Center for Toxicological Research, US Food and Drug Administration

• SAHIN Nurhan

  Department of Animal Nutrition, Faculty of Veterinary Science, Firat University

• SAHIN Kazim

  Department of Animal Nutrition, Faculty of Veterinary Science, Firat University

• ONDERCI Muhittin

  Veterinary Control and Research Institute

• PRASAD Ananda

  Karmanos Cancer Institute, Wayne State University

• KUCUK Omer

  Karmanos Cancer Institute, Wayne State University

• Kucuk Omer

  Karmanos Cancer Institute Wayne State University

• Sahin Kazim

  Department Of Animal Nutrition Faculty Of Veterinary Science Firat University

• Sahin Nurhan

  Department Of Animal Nutrition Faculty Of Veterinary Science Firat University

• Prasad Ananda

  Karmanos Cancer Institute Wayne State University

• Doerge Daniel

  National Toxicological Research Center Us Fda

• Doerge Daniel

  National Center For Toxicological Research U.s. Food And Drug Administration

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