In Vitro and in Vivo Antimicrobial Action of Tea : The Commonest Beverage of Asia(Miscellaneous)
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概要
- 論文の詳細を見る
The methanolic extract of leaves of Camellia sinensis (L) O. KUNTZE was screened for antimicrobial property against 111 bacteria comprising 2 genera of Gram positive and 7 genera of Gram negative bacteria. Most of these strains were inhibited by the compound at 10-50μg/ml level and few strains were sensitive even at lower concentrations (5μg/ml). The bacteria could be arranged in the decreasing order of sensitivity towards the compound in the following manner : Staphylococcus aureus, Vibrio cholerae, Escherichia coli, Shigella spp., Salmonella spp., Bacillus spp., Klebsiella spp. and Pseudomonas aeruginosa. The antibacterial activity of compound could also be confirmed in vivo. When it was given to Swiss strain of white mice at different dosages (30, 60μg/mouse), it could significantly protect the animals challenged with 50MLD of Salmonella typhimurium NCTC 74. According to Chi square test the in vivo data were highly significant (p<0.001).
- 公益社団法人日本薬学会の論文
- 2005-11-01
著者
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Dasgupta Asish
インド
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Dastidar Sujata
Department Of Pharmaceutical Technology Jadavpur University
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BANDYOPADHYAY Durba
Department of Pharmaceutical Technology, Jadavpur University
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CHATTERJEE Tapan
Department of Pharmaceutical Technology, Jadavpur University
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DASGUPTA Asish
Department of Pharmaceutical Technology, Jadavpur University
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LOURDURAJA Jeyaseeli
Department of Pharmaceutical Technology, Jadavpur University
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Chatterjee Tapan
Department Of Pharmaceutical Technology Jadavpur University
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Lourduraja Jeyaseeli
Department Of Pharmaceutical Technology Jadavpur University
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Bandyopadhyay Durba
Department Of Pharmaceutical Technology Jadavpur University
関連論文
- In Vitro Biological Activity of Prenylflavanones
- In Vitro and in Vivo Antimicrobial Action of Tea : The Commonest Beverage of Asia(Miscellaneous)