Antimitotic and Antifungal C-3/C-3"-Biflavanones from Stellera chamaejasme

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概要

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• Two new C-3/C-3" biflavanones, chamaejasmenin D (1) and isochamaejasmenin B (2), were isolated from the roots of Stellera chamaejasme, together with five known biflavanones, chamaejasmenin A (3), chamaejasmenin B (4), neochamaejasmin A (5), sikokianin A (6), and chamaejasmenin C (7). Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. Among these compounds, 1-3 demonstrated potent antimitotic and antifungal activity with minimum inhibitory concentration (MIC) values of 6.25, 6.25, and 3.12μg/ml, respectively.

• 公益社団法人日本薬学会の論文
• 2005-07-01

著者

• Zhang Huiping

  Department Of Chemistry Of Natural Drugs School Of Pharmacy Fudan University

• YANG Guohong

  Department of Pharmacognosy, School of Pharmacy, Fudan University

• LIAO Zhixin

  Department of Pharmacognosy, School of Pharmacy, Fudan University

• XU Zhiyong

  Department of Chemistry of Natural Drugs, School of Pharmacy, Fudan University

• CHEN Daofeng

  Department of Pharmacognosy, School of Pharmacy, Fudan University

• Xu Zhiyong

  Department Of Chemistry Of Natural Drugs School Of Pharmacy Fudan University

• Liao Zhixin

  Department Of Pharmacognosy School Of Pharmacy Fudan University

• Chen Daofeng

  Department Of Pharmacognosy School Of Pharmacy Fudan University

• Yang Guohong

  Department Of Pharmacognosy School Of Pharmacy Fudan University

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