New Sphingolipids and a Sterol from a Lobophytum Species of the Indian Ocean

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概要

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• Chemical investigation of a soft coral species of the genus Lobophytum has resulted in the isolation of three new sphingolipids-(2S,3S,4R)-2-nonadecanoylamino-octadecane-1,3,4-triol (1), (2S,3R,4E,8E)-[(2'R)-2'-hydroxy-heptadecanoylamino]-4,8-octadecadiene-1,3-diol (2), 1-O-(β-D-glucopyranosyl)-(2S,3R,4E,8E)-2-[(2'R)-2'-hydroxynonadecanoylamino]-9-methyl-4,8-octadecadiene-1,3-diol (3) and a sterol-(24S)-ergost-5-en-3β,7β-diol (4) along with the known sphingolipid-(2S,3R,4E,8E)-2-hexadecanoylamino-4,8-octadecadien-1,3-diol (5) which showed cytotoxicity against human peripheral blood mononuclear cells (PBMC).

• 公益社団法人日本薬学会の論文
• 2005-02-01

著者

• RAO Desaraju

  Department of Pharmaceutical Sciences, Andhra University

• Rao Desaraju

  Department Of Pharmaceutical Sciences Andhra University

• Muralidhar Pendyala

  Department Of Pharmaceutical Sciences Andhra University

• KUMAR Muthyala

  Department of Pharmaceutical Sciences, Andhra University

• KRISHNA Nallamothu

  Department of Pharmaceutical Sciences, Andhra University

• RAO Chaganty

  Department of Organic Chemistry, Andhra University

• Rao Chaganty

  Department Of Organic Chemistry Andhra University

• Kumar Muthyala

  Department Of Pharmaceutical Sciences Andhra University

• Krishna Nallamothu

  Department Of Pharmaceutical Sciences Andhra University

関連論文

• Marine Sterols. XIX. Polyhydroxysterols of the Soft Corals of the Andaman and Nicobar Coasts. (3). Isolation and Structures of Five New C_ Polyhydroxysterols from Two Sclerophytum sp. Soft Corals
• Marine Sterols. XVII. : Polyhydroxysterols of the Soft Corals of the Andaman and Nicobar Coasts. : (2). Isolation and Structures of Three 16β-Hydroxy Steroidal Glycosides from an Alcyonium sp. Soft Coral
• New Sphingolipids and a Sterol from a Lobophytum Species of the Indian Ocean
• New Sphingolipids from Marine Sponge Iotrochota baculifera

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