LC-MS/MS analysis of dextromethorphan metabolism in human saliva and urine to determine CYP2D6 phenotype and individual variability in N-demethylation and glucuronidation

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概要

• 論文の詳細を見る
• 2004-11-25

著者

• Lutz Werner

  Department Of Toxicology University Of Wurzburg

• Lutz Ursula

  Department Of Toxicology University Of Wurzburg

• VOLKEL Wolfgang

  Department of Toxicology, University of Wurzburg

• LUTZ Roman

  Seminar for Statistics, Swiss Federal Institute of Technology

• Lutz Roman

  Seminar For Statistics Swiss Federal Institute Of Technology

• Lutz Roman

  Seminar For Statistics

• Volkel Wolfgang

  Department Of Toxicology University Of Wurzburg

関連論文

• Simultaneous determination of O^6-methyl-2'-deoxyguanosine, 8-oxo-7,8-dihydro-2'-deoxyguanosine, and 1,N^6-etheno-2'-deoxyadenosine in DNA using on-line sample preparation by HPLC column switching coupled to ESI-MS/MS
• LC-MS/MS analysis of dextromethorphan metabolism in human saliva and urine to determine CYP2D6 phenotype and individual variability in N-demethylation and glucuronidation
• Quantification of cortisol and 6 beta-hydroxycortisol in human urine by LC-MS/MS, and gender-specific evaluation of the metabolic ratio as biomarker of CYP3A activity
• Metabolite profiling in human urine by LC-MS/MS : Method optimization and application for glucuronides from dextromethorphan metabolism

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