Differences in Fragmentation between [M+H]^+ and [M+Li]^+ Ions in Fast Atom Bombardment Mass Spectrometry

概要

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In order to understand differences in fragmentation between [M+H]+ and [M+A]+ ions (A=Li, Na, K, Rb, and Cs) in more detail, dissociation reactions of [M+H]+ and [M+Li]+ ions of N-t-butoxycarbonyl (Boc)-α-methylalanine (BMA) and N-t-Boc-α-methylalanine methyl ester (BMAM) in fast atom bombardment mass spectrometry (FAB-MS) were examined. Fragmentation and structural features of the [M+H]+ and [M+Li]+ ions are interpreted by using tandem mass spectrometry (MS/MS). The order of the activity of dissociation reaction [M+H]+[M+Li]+ is suggested from the relative peak intensities in the FAB mass spectra, I[M+H-fragment]+/I[M+H]+ and I[M+Li-fragment]+/I[M+Li]+. Furthermore, MNDO optimized structures of the [M+H]+ and [M+Li]+ ions are compared with the structures of the [M+H]+ and [M+Li]+ ions proposed by FAB-MS.
日本質量分析学会の論文
1997-02-01