Hypercalcemia in a Patient with Primary Hyperparathyroidism and Acromegaly : Distinct Roles of Growth Hormone and Parathyroid Hormone in the Development of Hypercalcemia
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概要
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We herein report a case of primary hyperparathyroidism associated with acromegaly. Although serum parathyroid hormone (PTH) levels increased after the resection of a pituitary adenoma, levels of serum 1á, 25-dihydroxyvitamin D [1, 25(OH)2D] decreased but remained above the normal upper limit. After resection of a parathyroid adenoma, serum PTH, 1, 25(OH)2D, calcium (Ca), and phosphate were all normalized. Since serum 1, 25(OH)2D levels decreased in spite of the increase in serum PTH levels after normalization of levels of growth hormone (GH), GH may have contributed to the elevation of serum 1, 25(OH)2D. It is therefore suggested that the mechanism by which elevation of serum 1, 25(OH)2D occurred in the present case may involve an increase in serum GH distinct from the PTH-mediated pathway.
- 2005-04-01
著者
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Inaba Masaaki
Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School Of Medicine
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Inaba Masaaki
Department Of Endocrinology Metabolism And Molecular Medicine Osaka City University Graduate School
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Inaba Masaaki
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School
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Nishizawa Yoshiki
Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate Schoo
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IMANISHI YASUO
Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate Schoo
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Imanishi Yasuo
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School
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Tahara Hideki
Department Of Endocrinology Metabolism And Molecular Medicine Osaka City University Graduate School
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Tahara Hideki
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School
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Inaba Munemichi
The Fourth Department Of Medicine Saitama Medical School
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Nishizawa Yoshiki
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School
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Goto Hitoshi
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School
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UEDA Misako
Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate Schoo
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Na Y
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School
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Ueda Misako
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School
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Imanishi Yasuo
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School
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Goto Hitoshi
Department Of Applied Physics Faculty Of Engineering Fukui University:toyota Motor Co.
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Nishizawa Yoshiki
Department Of Metabolism Endocrinology And Molecular Medicine Osaka City University Graduate School Of Medicine
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