BY55/CD160 acts as a co-receptor in TCR signal transduction of a human circulating cytotoxic effector T lymphocyte subset lacking CD28 expression

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2002-05-01

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Multiple co-stimulatory signals are required for triggering proliferation of T cells from human secondary lymphoid tissue
Activation signals are deliverd through two distinct epitopes of CD100, a unique 150 kDa human lymphocyte surface structure previously defined by BB18 mAb
Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively
BY55/CD160 acts as a co-receptor in TCR signal transduction of a human circulating cytotoxic effector T lymphocyte subset lacking CD28 expression
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