Clinical Economics in Clinical Trials : The Measurement of Cost and Outcomes in the Assessment of Clinical Services through Clinical Trials

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概要

• 論文の詳細を見る

• As the population ages and more expensive high-technology services become available, health care costs continue to spiral upward. Because the financial resources for health care are limited, economic analysis can help to evaluate expenditures and set priorities. Economic analysis of medical technology or medical care evaluates a medical service by comparing its dollar cost with its dollar benefit (cost-benefit), by measuring its dollar cost in relation to its outcomes (cost-effectiveness) as well as in relation to its utility or quality-adjusted outcomes (cost-utility), or simply by tabulating the costs involved (cost-identification). Direct costs are generated as services are provided. In addition, patients productivity is affected, and these costs can be considered, especially in determining the benefit of a service that decreases morbidity or mortality. Intangible costs are those of pain, suffering, and grief. The point of view, or perspective, of the study determines the costs and benefits that will be measured in the analysis. Sensitivity analysis, which can evaluate the stability of the conclusions to the data used, is an important assessment within economic analysis. Economic analysis of new pharmaceutical therapies is increasingly being incorporated into clinical trials. Although there are some limitations of pharmacoeconomic information in clinical studies of drug safety and efficacy, these trials are often the only opportunity for economic data collection before adoption and reimbursement decisions are made. Validation after the drug has been introduced should complement economic information developed from clinical trials.

• The Keio Journal of Medicineの論文
• 1999-03-01

著者

• Ohishi Akira

  The Clinical Economics Research Unit Department Of Medicine Georgetown University Medical Center

• SCHULMAN Kevin

  The Clinical Economics Research Unit, Department of Medicine, Georgetown University Medical Center

• PARK Jaewon

  Department of Internal Medicine, Tokyo Daini National Hospital

• GLICK Henry

  Division of General Internal Medicine and the Leonard Davis Institute of Health Economics, Universit

• EISENBERG John

  Agency for Health Care Policy and Research, US Department of Health and Human Services

• Park Jaewon

  Department Of Internal Medicine Tokyo Daini National Hospital

• Glick Henry

  Division Of General Internal Medicine And The Leonard Davis Institute Of Health Economics University

• Schulman Kevin

  The Clinical Economics Research Unit Department Of Medicine Georgetown University Medical Center

• Eisenberg John

  Agency For Health Care Policy And Research Us Department Of Health And Human Services

• PARK Jaewon

  Department of Information and Communication Engineering, Yeungnam University

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