Non-secretory Multiple Myeloma with Azurophilic Granules and Vacuoles : An Immunological and Ultrastructural Study
スポンサーリンク
概要
- 論文の詳細を見る
Cytoplasmic vacuolation was seen in patients with a variety of plasma cell dyscrasia. We report here a case of leukemic non-secretory multiple myeloma with many azurophilic granules. By electron microscopy, the myeloma cells were found to have a well-developed rough endoplasmic reticulum and a clear Golgi apparatus, and azurophilic granules were identified as phagocytic vacuoles. In addition to myeloma markers, the cells were positive for B cell-associated, myeloid and stem cell markers. The diagnosis is difficult because of its misleading morphology and unusual surface markers. We consider that electron microscopy is useful for the identification of cell lineage in this disorder.
- 社団法人 日本内科学会の論文
- 2004-07-01
著者
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KUYAMA Jun
Department of Internal Medicine, Toyonaka Municipal Hospital
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KOSUGI Satoru
Department of Internal Medicine and Molecular Science, Graduate School of Medicine, Osaka University
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TAKE Hironori
Department of Internal Medicine, Toyonaka Municipal Hospital
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KANAYAMA Yoshio
Department of Internal Medicine, Ashiya Municipal Hospital
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Matsuyama Takaharu
Japanese Red Cross Nagoya First Hospital
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MATSUYAMA Tatsuo
Department of Internal Medicine, Toyonaka Municipal Hospital
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Kuyama Jun
Department Of Internal Medicine Toyonaka Municipal Hospital
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Kosugi S
Department Of Hematology And Oncology Graduate School Of Medicine Osaka University
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Take Hironori
Department Of Internal Medicine Toyonaka Municipal Hospital
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Kanayama Yoshio
Department Of Internal Medicine Ashiya Municipal Hospital
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Kosugi Satoru
Department of Hematology and Oncology, Graduate School of Medicine, Osaka University
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