Therapy-related Myelodysplastic Syndrome with Trisomy 1q due to der (1 ; 7) and Megakaryoblastic Proliferation Developing during Complete Remission of Therapy-related Acute Myeloid Leukemia with t(8 ; 21)
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概要
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Therapy-related acute myeloid leukemia (t-AML) with t(8;21) and therapy-related myelodysplastic syndrome (t-MDS) with trisomy 1q due to der(1;7) developed in the same patient with T-cell lymphoma at intervals of six years. After the development of t-MDS with trisomy 1q, during complete remission of t-AML, the number of megakaryoblasts increased to maximally 74% of leukocytes in the blood. This is a very rare case of two separate therapy-related myeloid malignancies (early t-AML and late t-MDS) and is also a notable case of t-MDS with trisomy 1q due to der(1;7) accompanied by megakaryoblastic proliferation.
- 2004-07-01
著者
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Kumagai Kyoya
Division Of Hematology-oncology Chiba Cancer Center Hospital
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Kumagai Kyoya
Division Of Hematology And Chemotherapy Chiba Cancer Center
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Ishii Akihiro
Division Of Hematology-oncology Chiba Cancer Center Hospital
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Ishii Akihiro
Division Of Hematology And Oncology Chiba Cancer Center Hospital
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MATSUBAYASHI Keiko
Department of Neurosurgery, Osaka Red Cross Hospital
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Sakai Chikara
Division Of Hematology And Chemotherapy Chiba Cancer Center Hospital
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Saotome Takashi
Division Of Hematology-oncology Chiba Cancer Center Hospital
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Matsubayashi Keiko
Department Of Clinical Laboratory Chiba Cancer Center Hospital
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