遷移金属触媒を用いる炭素-炭素不飽和結合のカルボスタニル化反応に関する研究
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概要
- 論文の詳細を見る
Carbometalation of alkynes produces <I>cis</I>-substituted alkenylmetals and is an extremely useful method for a stereoselective olefin synthesis, since the resulting alkenylmetals can be transformed further to variously substituted ethenes. We have been disclosing diverse types of transition metal-catalyzed carbostannylations of alkynes, 1, 3-dienes and 1, 2-dienes, featuring much higher chemoselectivity compared with the previously reported carbometalations with more nucleophilic organometallic compounds. Alkynyl- and allylstannylations of alkynes were catalyzed by a palladium complex with or without iminophosphine ligand, whereas nickel complexes catalyzed the addition of alkynyl-, allyl- and acylstannanes. Nickel catalysts were found to be effective also for acyland alkynylstannylations of 1, 3- and 1, 2-dienes. The carbostannylation of alkynes in the presence of a palladium-diimine complex was accompanied by dimerization of alkynes, where the carbon-tin bond of alkynyl-, alkenyl-, allyl-, aryl- and heteroarylstannanes accepted insertion of two molecules of an alkyne.
- 社団法人 有機合成化学協会の論文
- 2004-06-01