Features of Hepatitis E Virus Infection in Japan
スポンサーリンク
概要
- 論文の詳細を見る
Hepatitis E virus (HEV) is a major cause of acute hepatitis in many developing countries. HEV is transmitted principally by the fecal-oral route, and water-borne epidemics are characteristic of hepatitis E. Recently, there is growing consensus that HEV-associated hepatitis also occurs among individuals in industrialized nations who had no history of travel to endemic areas. Zoonotic spread of HEV has been suggested as human and swine HEV strains are closely related genetically and experimental cross-species infection of swine HEV to a chimpanzee and that of human HEV to swine have been demonstrated. This review describes the clinical, epidemiological and virological characteristics of domestic HEV infection in Japan, the genetic relatedness of Japanese human and swine HEV strains, and possible modes of HEV transmission, emphasizing that HEV should be considered in the diagnosis of acute or fulminant hepatitis of non-A, non-B, non-C etiology, even in patients who have not traveled abroad.(Internal Medicine 42: 1065-1071, 2003)
- 社団法人 日本内科学会の論文
- 2003-11-01
著者
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TAKAHASHI Masaharu
Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medic
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OKAMOTO Hiroaki
Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medic
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Nishizawa Tsutomu
Division Of Virology Department Of Infection And Immunity Jichi Medical School
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Okamoto Hiroaki
Division Of Virology Department Of Infection And Immunity Jichi Medical School
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Takahashi Masaharu
Division Of Virology Department Of Infection And Immunity Jichi Medical School
関連論文
- Sporadic acute hepatitis E occurred constantly during the last decade in northeast Japan
- A male patient with severe acute hepatitis who was domestically infected with a genotype H hepatitis B virus in Iwate, Japan
- A case of acute hepatitis E associated with multidrug hypersensitivity and cytomegalovirus reactivation
- Epidemiological and clinical study of sporadic acute hepatitis E caused by indigenous strains of hepatitis E virus in Japan compared with acute hepatitis A
- A Patient with Clinical Features of Acute Hepatitis E Viral Infection and Autoimmune Hepatitis
- Nucleotide Substitutions of Hepatitis E Virus Genomes Associated with Fulminant Hepatitis and Disease Severity
- Evolution in the hypervariable region of the hepatitis C virus in two infants infected by mother-to-infant transmission
- NO EVIDENCE FOR PATIENT-TO-PATIENT TRANSMISSION OF HEPATITIS C VIRUS DURING UPPER GASTROINTESTINAL ENDOSCOPY : MOLECULAR STUDIES ON THREE ACUTE HEPATITIS C PATIENTS
- IgM-class antibodies to TT virus (TTV) in patients with acute TTV infection
- A unique set of mutations in the 'preX' region of hepatitis B virus DNA frequently foun in patients but not in asymptomatic carriers: implication for a novel variant
- Sporadic acute hepatitis E of a 47-year-old man whose pet cat was positive for antibody to hepatitis E virus
- Possible association of vigorous hepatitis B virus replication with the development of fulminant hepatitis
- Persistence of hepatitis B viremia after recovery from acute hepatitis B : correlation between anti-HBc titer and HBV DNA in serum
- Features of Hepatitis E Virus Infection in Japan
- Three male patients with sporadic acute hepatitis E in Sendai, Japan, who were domestically infected with hepatitis E virus of genotype III or IV