A New Method of Inhalation Anesthesia with Nasopharyngeal Insufflation in Rat Experiment

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概要

• 論文の詳細を見る

• We have established a new method of anesthesia with nasopharyngeal insufflation for intraoral procedure in rodents. Twelve male Wistar rats weighing 330-390 g were used in this study. Insertion of a feeding tube 1.0 mm in diameter coated with 2% xylocaine jelly was inserted into the nasal cavity approximately 25 mm from the naris, and anesthetization with mixed gas of 100% oxygen with 3-4% enflurane at 0.25-0.5 l/min flow rate was achieved. Using this anesthetic method, a chronic experiment comprising 1-h/day experimental procedure was carried out for 14 days. This method enabled, 1) simple and safe operation of the induction, emergence and anesthetic depth, 2) experimental procedures on the dental/oral region, 3) avoidance of the dyspnea and tachypnea, and 4) avoidance of cumulative effects in daily anesthesia.

• 社団法人　日本実験動物学会の論文
• 2003-07-01

著者

• Kamimura Ryozo

  Institute Of Laboratory Animal Sciences Faculty Of Medicine Kagoshima University

• KUROE Kazuto

  Department of Orthodontics, Kagoshima University Dental School

• Kuroe Kazuto

  Department Of Orthodontics Kagoshima University Dental School

• YAMASAKI Konosuke

  Department of Orthodontics, Kagoshima University Dental School

• Yamasaki K

  Kyoto Univ. Kyoto Jpn

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