Analysis of the Gene Encoding Copper/Zinc Superoxide Dismutase Homolog in Dictyostelium discoideum

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概要

• 論文の詳細を見る

• SodD, a Cu/Zn superoxide dismutase in Dictyostelium discoideum, shows 48% identity to the cytosolic Cu/Zn superoxide dismutase (SOD) of Saccharomyces cerevisiae (SOD1). The sodD gene is expressed in D. discoideum cells at late-developmental stages. However, gene expression was not detected in the sporeless mutant, indicating that sodD is a spore cell-specific gene. The D. discoideum mutant, in which sodD was disrupted, grew and formed a multicellular structure normally, therefore the gene is not essential for growth and development. The mutant spores were sensitive to UV-light compared to the wild-type spores, indicating that SodD protects spores from cellular damage caused by UV-light.

• 公益社団法人　日本薬学会の論文
• 2002-12-01

著者

• Tsuji Atsushi

  Division Of Bioengineering Faculty Of Engineering Toyama University

• AKAZA YUYA

  Division of Bioengineering, Faculty of Engineering, Toyama University

• Yasukawa Hiroo

  Division Of Bioengineering Faculty Of Engineering Toyama University

• Akaza Yuya

  Division Of Bioengineering Faculty Of Engineering Toyama University

関連論文

• Expression of Genes Coding for Cell-Cell Adhesion Proteins in Dictyostelium discoideum Mutants that Form Small Fruiting Bodies
• Multinucleation of the sodC-Deficient Dictyostelium discoideum(Biochemistry/Molecular Biology)
• Myb-binding site regulates the expression of glucosamine-6-phosphate isomerase in Dictyostelium discoideum
• Two cell-counting factors regulate the aggregate size of the cellular slime mold Dictyostelium discoideum
• Analysis of the Gene Encoding Copper/Zinc Superoxide Dismutase Homolog in Dictyostelium discoideum

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