PTHrP-producing Tumor: Squamous Cell Carcinoma of the Liver Accompanied by Humoral Hypercalcemia of Malignancy, Increased IL-6 and Leukocytosis
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概要
- 論文の詳細を見る
A 77-year-old man was admitted to our hospital showing symptoms of general fatigue and appetite loss. He had leukocytosis, thrombocytosis and hypercalcemia with elevated serum levels of parathyroid hormone related peptide (PTHrP) and interIeukin-6 (IL-6). An increase in tumor markers SCC and CYFURA21-1 was observed. The liver contained a huge tumor, which was proved to be PTHrP producing squamous cell carcinoma by immuno-histochemical analysis. Since the tumor did not express IL-6, it was assumed to be induced by PTHrP in osteoblasts. This is the first report of PTHrP producing squamous cell carcinoma of the liver.(Internal Medicine 41: 371-376, 2002)
- 社団法人 日本内科学会の論文
- 2002-05-01
著者
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Matsuda Masahiro
The Department of Surgery
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NAKAMURA Fumiaki
The Division of Cardiology,Sakurabashi Watanabe Hospital
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MIYASHITA Yoshihiro
the Department of Medicine III
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MORIMOTO Yasuhiko
Department of Medicine, Aizenbashi Hospital
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Matsumoto Ikuko
The Department Of Internal Medicine Aizenbashi Hospital
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Kouhara Haruhiko
Department Of Molecular Medicine Osaka University Graduate School Of Medicine
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Nakamura Fumiaki
The Department Of Internal Medicine Aizenbashi Hospital
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Kouhara Haruhiko
Department Of Medicine Osaka University Graduate School Of Medicine
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Asanuma Nobuyuki
Department Of Medicine Osaka University Graduate School Of Medicine
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ASANUMA Nobuyuki
The Department of Internal Medicine, Aizenbashi Hospital
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HAGIWARA Keisuke
The Department of Internal Medicine, Aizenbashi Hospital
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KOUHARA Haruhiko
Endocrinology, Osaka University Hospital
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MIYAMOTO Makoto
Pathology, Osaka University Hospital
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NOGUCHI Sanai
The Department of Internal Medicine, Aizenbashi Hospital
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MORIMOTO Yasuhiko
The Department of Internal Medicine, Aizenbashi Hospital
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Morimoto Yasuhiko
Department Of Medicine Aizenbashi Hospital
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Morimoto Yasuhiko
Department Of Internal Medicine Aizenbashi Hospital
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Noguchi Sanai
The Department Of Internal Medicine Aizenbashi Hospital
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Miyashita Yoshihiro
The Department Of Internal Medicine Aizenbashi Hospital
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Matsuda Masahiro
The Department Of Internal Medicine Aizenbashi Hospital
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Asanuma Nobuyuki
Department Of Molecular Medicine Osaka University Medical School
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Kouhara Haruhiko
Department Of Molecular Medicine Osaka University Medical School
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Hagiwara Keisuke
The Department Of Internal Medicine Aizenbashi Hospital
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Miyamoto Makoto
Pathology Osaka University Hospital
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- PTHrP-producing Tumor: Squamous Cell Carcinoma of the Liver Accompanied by Humoral Hypercalcemia of Malignancy, Increased IL-6 and Leukocytosis